Bis(2-dimethylaminoethyl) ether Chemical Properties

Boiling point:

189 °C/760 mmHg

Density 

0.841 g/mL at 25 °C

vapor pressure 

49Pa at 20℃

refractive index 

n 20/D 1.430

Flash point:

151 °F

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

Soluble in water

form 

clear liquid

pka

9.12±0.28(Predicted)

color 

Colorless to Light yellow

Water Solubility 

100g/L at 20℃

BRN 

1739668

Exposure limits

ACGIH: TWA 0.05 ppm; STEL 0.15 ppm (Skin)

InChI

1S/C8H20N2O/c1-9(2)5-7-11-8-6-10(3)4/h5-8H2,1-4H3

InChIKey

GTEXIOINCJRBIO-UHFFFAOYSA-N

SMILES

CN(C)CCOCCN(C)C

LogP

-0.34 at 20℃

CAS DataBase Reference

3033-62-3(CAS DataBase Reference)

NIST Chemistry Reference

Ethanamine, 2,2'-oxybis[N,N-dimethyl-(3033-62-3)

EPA Substance Registry System

Bis[2-(dimethylamino)ethyl]ether (3033-62-3)

Safety Information

Hazard Codes 

T

Risk Statements 

20-22-24-34

Safety Statements 

26-36/37/39-45

RIDADR 

UN 2927 6.1/PG 2

WGK Germany 

2

RTECS 

KR9460000

TSCA 

TSCA listed

HazardClass 

3

PackingGroup 

III

HS Code 

29221990

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials

Hazard Classifications

Acute Tox. 3 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Dam. 1
Skin Corr. 1B

Hazardous Substances Data

3033-62-3(Hazardous Substances Data)

Toxicity

LD50 orl-rat: 1070 mg/kg JTOTDO 5,3,86

MSDS

• Language:English Provider:Bis(2-dimethylaminoethyl) ether
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

Bis(2-dimethylaminoethyl) ether Usage And Synthesis

Chemical Properties

Colorless and transparent liquid or Brown liquid. Soluble in water, easily soluble in alcohol, benzene, etc.

Uses

Bis(2-dimethylaminoethyl) ether is an efficient tertiary amine catalyst, which is suitable for the production of almost all foam products, mainly for the production of flexible foam products, especially for high resilience and RIM products. It is characterized by high catalytic activity, smooth foaming, large tolerance to tin, easy to adjust the formulation, and the physical and chemical properties of products produced with it, such as resilience and elongation, are better than other products.

Preparation

The main methods for the synthesis of Bis(2-dimethylaminoethyl) ether are:
(1) reaction of sodium dimethylaminoethanol and SO3 or chlorosulfonic acid;
(2) Reaction of trimethylamine with dichloroethyl ether or dimethylaminoethoxyethyl ether;
(3) One-step synthesis of dimethylamine and monoethyleneglycol under solid catalyst.

Application

Bis(2-dimethylaminoethyl) Ether (Potassium Clavulanate EP Impurity M) is used in the manufacturing of flexible polyurethane foams.

General Description

Bis(2-(dimethylamino)ethyl)ether appears as a clear or yellow liquid. Bp: 188°C. Toxic by inhalation, by skin absorption, ingestion, and eye contact.

Reactivity Profile

Bis (2-(dimethylamino)ethyl)ether reacts as a base. Reacts exothermically with acids. May form explosive peroxides upon exposure to the air.

Safety Profile

Poison by skin contact.Moderately toxic by ingestion. Experimental reproductiveeffects. A severe skin and eye irritant.

Toxics Screening Level

The initial threshold screening level (ITSL) for bis(2-dimethylaminoethyl)ether is 0.3 μg/m3 (based on an annual averaging time).

Bis(2-dimethylaminoethyl) ether(3033-62-3)Related Product Information

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