Basic information Safety Supplier Related

5,2'-O-Dimethyluridine

Basic information Safety Supplier Related

5,2'-O-Dimethyluridine Basic information

Product Name:
5,2'-O-Dimethyluridine
Synonyms:
  • 5,2'-O-Dimethyluridine
  • 5-METHYL-2'-O-METHYLURIDINE
  • 2'-O-METHYL-5-METHYLURIDINE
  • 2'-O-METHYLRIBOTHYMIDINE
  • 55486-09-4 2'-O-Methyl-5-methyluridine 4518
  • 5-Me -2'-OMe Uridine
  • 5-M-2‘-OMeUridine
  • Uridine,5-methyl-2'-O-methyl-
CAS:
55486-09-4
MF:
C11H16N2O6
MW:
272.25
EINECS:
2017-001-1
Product Categories:
  • 55486-09-4
Mol File:
55486-09-4.mol
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5,2'-O-Dimethyluridine Chemical Properties

Melting point:
183-186°C
Density 
1.47±0.1 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly, Sonicated)
pka
9.55±0.10(Predicted)
form 
Solid
color 
White to Off-White
CAS DataBase Reference
55486-09-4(CAS DataBase Reference)
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5,2'-O-Dimethyluridine Usage And Synthesis

Description

5-Me-2'-OMe Uridine is one of three oligonucleotide in platinum-derivatized homopyrimidine triplex-forming oligonucleotides (Pt-TFOs) useful in crosslinking to the transcribed strand in the human androgen receptor (AR) gene. Inhibitory activity against M. bovis and M. avium.

Uses

5-Methyl-2’-O-methyluridine is one of three oligonucleotide in platinum-derivatized homopyrimidine triplex-forming oligonucleotides (Pt-TFOs) useful in crosslinking to the transcribed strand in the human androgen receptor (AR) gene. Inhibitory activity against M. bovis and M. avium.

Definition

ChEBI: A methyluridine that consists of uridine bearing two methyl substituents located at position C-5 on the uracil ring and position O-2' on the ribose ring.

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