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Quercetin dihydrate

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Quercetin dihydrate Basic information

Product Name:
Quercetin dihydrate
Synonyms:
  • QUERCETIN DIHYDRATE
  • 3,5,7,3',4'-PENTAHYDROXYFLAVONE DIHYDRATE
  • 3,3’,4’,5,7-pentahydroxy-flavondihydrate
  • Flavone,3,3’,4’,5,7-pentahydroxy-,dihydrate
  • 2-(3,4-DIHYDROXYPHENYL)-3,5,7-TRIHYDROXY-4H-1-BENZOPYRAN-4-ONE DIHYDRATE
  • 3,3',4',5,7-PENTAHYDROXYFLAVONE 2H2O
  • 3,3',4',5,7-PENTAHYDROXYFLAVONE DIHYDRATE
  • 3,3',4',5,7-PENTAHYDROXYFLAVONE HYDRATE
CAS:
6151-25-3
MF:
C15H14O9
MW:
338.27
EINECS:
612-158-3
Product Categories:
  • Flavanols
  • Biochemistry
  • Flavonoids
  • C15 to C38
  • Carbonyl Compounds
  • Ketones
  • Signalling
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Tyrosine Kinase Inhibitors
  • Inhibitors
  • TROXEPURE
Mol File:
6151-25-3.mol
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Quercetin dihydrate Chemical Properties

Melting point:
>300 °C(lit.)
Density 
1.680 g/cm3
storage temp. 
-20°C
solubility 
Soluble in DMSO > 10 mM
form 
Yellow solid
Colour Index 
75670
color 
Yellow
Water Solubility 
practically insoluble
Merck 
14,8034
BRN 
317313
InChIKey
GMGIWEZSKCNYSW-UHFFFAOYSA-N
LogP
2.075 (est)
CAS DataBase Reference
6151-25-3(CAS DataBase Reference)
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Safety Information

Hazard Codes 
T
Risk Statements 
25-46-23/24/25
Safety Statements 
45-53
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
3
RTECS 
LK8950000
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
III
HS Code 
29329990
Toxicity
LD50 orally in mice: 160 mg/kg (Sullivan)

MSDS

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Quercetin dihydrate Usage And Synthesis

Chemical Properties

yellow crystalline powder

Uses

capillary protectant, antioxidant. antineoplastic, anti-HIV

Uses

bioflavenoid, antioxidant, antiviral, antimicrobial, enzyme inhibitor

Uses

Quercetin dihydrate used as a Inhibitor of protein tyrosine kinase, mitochondrial ATPase and phosphodiesterase inhibitor. It Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity.

General Description

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Biochem/physiol Actions

Quercetin dihydrate is a flavonoid with anticancer activity. Quercetin is a mitochondrial ATPase and phosphodiesterase inhibitor. It Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity. Quercetin has antiproliferative effects on cancer cell lines, reduces cancer cell growth via type II estrogen receptors, and arrests human leukemic T cells in late G1 phase of the cell cycle.

target

HMG-CoA Reductase | SOD | Antifection

storage

Room temperature

Purification Methods

Crystallise the flavone from aqueous EtOH and dry at 100o. It also sublimes in a vacuum. IR: 2.5 and 16.7 (KBr). max It complexes with Cu2+, Al3+, Ca2+, Ge4+, Zn2+, Ti4+, Zr4+, Th4+, UO4+ . [Beilstein 18 H 242, 18 I 242, 18 II 236, 18 III/IV 3470, 18/5 V 494.]

Quercetin dihydrateSupplier

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