TETRAGLYCINE
TETRAGLYCINE Basic information
- Product Name:
- TETRAGLYCINE
- Synonyms:
-
- Glycine tetrapeptide
- NSC 89178
- etraglycine
- Gly-Gly-Gly-Gly-OH≥ 99% (TLC)
- TETRAGLYCINE
- TRIGLYCYL-GLYCINE
- ([(([(Aminoacetyl)amino]acetyl)amino)acetyl]amino)acetic acid
- Glycine, N-[N-(N-glycylglycyl)glycyl]-
- CAS:
- 637-84-3
- MF:
- C8H14N4O5
- MW:
- 246.22
- EINECS:
- 211-303-4
- Product Categories:
-
- Biochemistry
- Oligopeptides
- Peptide Synthesis
- Mol File:
- 637-84-3.mol
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TETRAGLYCINE Chemical Properties
- Melting point:
- 300 °C
- Boiling point:
- 389.22°C (rough estimate)
- Density
- 1.3853 (rough estimate)
- refractive index
- 1.6590 (estimate)
- storage temp.
- −20°C
- pka
- 3.32±0.10(Predicted)
- form
- powder to crystal
- color
- White to Almost white
- BRN
- 1715387
- CAS DataBase Reference
- 637-84-3(CAS DataBase Reference)
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Safety Information
- Safety Statements
- 24/25
- WGK Germany
- 3
- HS Code
- 2924.19.8000
MSDS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ACROS
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TETRAGLYCINE Usage And Synthesis
Chemical Properties
white powder
Uses
peptide synthesis
Biological Activity
Tetraglycine is used with copper (Cu-II) to study mechanisms of hydrogen peroxide/bicarbonate free radical production and effect in vitro.
in vivo
Tetraglycine and Triglycine (1.0 μmol glycine/g body wt (246.22 mg/kg), injected into a central vein) results in greater glycine concentration in the kidney than injection of either Glycine.html" class="link-product" target="_blank">Glycine (HY-Y0966) or Diglycine[1].
| Animal Model: | Male Sprague-Dawley rats (270-300 g)[1] |
| Dosage: | 1.0 μmol glycine/g body wt (246.22 mg/kg) |
| Administration: | IV, injected over a period of 30 s |
| Result: | Five minutes after the Tetraglycine injection, there were accumulations of diglvcine, triglvcine, and Tetraglycine in the kidney. |
Purification Methods
Crystallise it from H2O (optionally, by the addition of EtOH). [Li et al. J Am Chem Soc 79 5859 1957, Rising et al. J Am Chem Soc 56 1179 1934, Beilstein 4 II 807, 4 III 1201, 4 IV 2472.]
TETRAGLYCINESupplier
J & K SCIENTIFIC LTD.
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- 18210857532
- jkinfo@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
- Tel
- 021-61259108 18621169109
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- 821-50328103-801 18930552037
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TCI (Shanghai) Development Co., Ltd.
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- 021-67121386
- Sales-CN@TCIchemicals.com
Energy Chemical
- Tel
- 021-021-58432009 400-005-6266
- sales8178@energy-chemical.com
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