Methyl 4-hydroxycinnamate Chemical Properties

Melting point:

144-145°

Boiling point:

306.6±17.0 °C(Predicted)

Density 

1?+-.0.06 g/cm3(Predicted)

vapor pressure 

0.056Pa at 25℃

storage temp. 

Inert atmosphere,Room Temperature

pka

8.82±0.13(Predicted)

form 

crystals

color 

White

Water Solubility 

5.332g/L at 25℃

LogP

1.88 at 25℃

CAS DataBase Reference

3943-97-3(CAS DataBase Reference)

NIST Chemistry Reference

2-Propenoic acid, 3-(4-hydroxyphenyl)-, methyl ester(3943-97-3)

Safety Information

HazardClass 

IRRITANT

HS Code 

2916399090

Methyl 4-hydroxycinnamate Usage And Synthesis

Description

Methyl 4-hydroxycinnamate is an atifungal agent and a cinnamic acid derivative used in structure-antifungal activity relationship studies against Aspergillus flavus, Aspergillus terreus, and Aspergillus niger.

Occurrence

Methyl 4-hydroxycinnamate isolated from the herbs of Piper longum, Alpinia blepharocalyx, and Grevillea robusta.

Uses

3-(4-Hydroxyphenyl)-2-propenoic Acid Methyl Ester is used in the synthesis of AB3 and constitutional isomeric AB2 phenylpropyl ether-based supramolecular dendrimers. Also used in the synthesis of potent antagonists of leukotrines.

Definition

ChEBI: 4-coumaric acid methyl ester is a cinnamate ester that is the methyl ester of 4-coumaric acid. It has a role as a melanin synthesis inhibitor, a fungal metabolite, an anti-inflammatory agent, an antifungal agent and a plant metabolite. It is a cinnamate ester, a member of phenols and a methyl ester. It derives from a 4-coumaric acid.

Synthesis Reference(s)

Chemical and Pharmaceutical Bulletin, 28, p. 3662, 1980 DOI: 10.1248/cpb.28.3662

Methyl 4-hydroxycinnamate(3943-97-3)Related Product Information

• Methyl 4-hydroxycinnamate
• 4-(Trifluoromethyl)cinnamic acid
• alpha-Methylcinnamic acid
• Ethyl 4-methylcinnamate
• Basic Violet 1
• Kresoxim-methyl
• Methanol
• 3-Hydroxycinnamic acid
• Caffeic acid
• 2-HYDROXYCINNAMIC ACID
• METHYL 4-METHYLCINNAMATE
• Methyl cinnamate
• ETHYL COUMARATE
• Paraquat dichloride
• Methyl (R)-(-)-3-hydroxybutyrate
• 4-Hydroxycinnamic acid
• Methylparaben
• Cinnamic acid