LEUCOPTERIN
LEUCOPTERIN Basic information
- Product Name:
- LEUCOPTERIN
- Synonyms:
-
- 2-AMINO-4,6,7-TRIHYDROXYPTERIDINE
- LEUCOPTERIN
- 2-aminopteridine-4,6,7-triol
- 2-Amino-5,8-dihydropteridine-4,6,7(1H)-trione
- 2-amino-5,8-dihydro-1H-pteridine-4,6,7-trione
- 2-azanyl-5,8-dihydro-1H-pteridine-4,6,7-trione
- LEUCOPTERIN(RG)(DISCONTINUED)
- 4,6,7(3H)-Pteridinetrione, 2-amino-5,8-dihydro-
- CAS:
- 492-11-5
- MF:
- C6H5N5O3
- MW:
- 195.14
- EINECS:
- 207-747-3
- Product Categories:
-
- Heterocycles
- Mol File:
- 492-11-5.mol
LEUCOPTERIN Chemical Properties
- Melting point:
- 300 °C
- Boiling point:
- 331.78°C (rough estimate)
- Density
- 1.5875 (rough estimate)
- refractive index
- 1.8500 (estimate)
- solubility
- Aqueous Base (Slightly)
- form
- Solid
- pka
- 6.74±0.20(Predicted)
- color
- Pale Beige to Beige
- Water Solubility
- 1.333mg/L(22.5 ºC)
LEUCOPTERIN Usage And Synthesis
Uses
Leucopterin (cas# 492-11-5) is a useful research chemical. It is used in the methods of drug screening to identify compounds for treatment of protein trafficking diseases.
Definition
ChEBI: Leucopterin (enol form) is a member of the class of pteridines that is pteridine substituted by an amino group at position 2 and hydroxy groups at positions 4, 6 and 7. It has a role as a biological pigment. It is a member of pteridines, a heteroaryl hydroxy compound and a triol. It is a tautomer of a leucopterin (keto form).
Purification Methods
Leucopterin is purified by dissolving it in aqueous NaOH, stirring with charcoal, filtering and precipitating by adding aqueous HCl, then drying at 100o in a vacuum. It separates with 0.5 mole of H2O. Its solubility in H2O is 1g/750 litres [Albert et al. J Chem Soc 4219 1952, Albert & Wood J Appl Chem (London) 2 591 1952, Pfleiderer Chem Ber 90 2631 1957]. [Beilstein 26 III/IV 4017.]