alpha-Bisabolol
alpha-Bisabolol Basic information
- Product Name:
- alpha-Bisabolol
- Synonyms:
-
- (R*, R*)-alpha, 4-Dimethyl-alpha-(4-methyl-3-pentyl)cyclohex-3-en-1-methanol
- (R*,R*)-alpha-4-Dimethyl-alpha-(4-methyl-3-petenyl)-3-cyclohexene-1-methanol
- α-bisabolol,6-methyl-2-(4-methyl-3-cyclohexen-1-yl)-5-hepten-2-ol,dragosantol
- 3-Cyclohexene-1-methanol, .alpha.,4-dimethyl-.alpha.-(4-methyl-3-pentenyl)-, (.alpha.R,1R)-rel-
- 6-methyl-2-(4-methyl-3-cyclohexen-1-yl)-5-hepteno
- alpha-Bisabalol
- alpha-bisabolool
- Camilol
- CAS:
- 515-69-5
- MF:
- C15H26O
- MW:
- 222.37
- EINECS:
- 208-205-9
- Product Categories:
-
- Terpenes
- Terpenes (Others)
- Biochemistry
- 515-69-5
- Mol File:
- 515-69-5.mol
alpha-Bisabolol Chemical Properties
- Melting point:
- 25°C
- Boiling point:
- 154-156°C
- Density
- 0.93 g/mL at 20 °C(lit.)
- refractive index
- n20/D 1.496
- Flash point:
- 135°C
- storage temp.
- Refrigerator
- solubility
- Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
- pka
- 15.04±0.29(Predicted)
- form
- Liquid
- color
- Clear Colourless
- Odor
- at 100.00 %. mild floral peppery balsamic clean
- Odor Type
- floral
- Water Solubility
- Soluble in alcohol, natural, mineral and synthetic oils. Insoluble in water.
- Merck
- 14,1241
- BRN
- 5733954
- Stability:
- Stable. Combustible. Incompatible with strong oxidizing agents.
- LogP
- 5.63
- CAS DataBase Reference
- 515-69-5(CAS DataBase Reference)
- NIST Chemistry Reference
- «ALPHA»-bisabolol(515-69-5)
- EPA Substance Registry System
- 3-Cyclohexene-1-methanol, .alpha.,4-dimethyl-.alpha.-(4-methyl-3-pentenyl)-, (.alpha.R,1R)-rel- (515-69-5)
MSDS
- Language:English Provider:alpha,4-Dimethyl-alpha-(4-methyl-3-pentenyl)-3-cyclohexene-1-methanol
- Language:English Provider:ALFA
alpha-Bisabolol Usage And Synthesis
Chemical Properties
colourless to faintly yellow viscous liquid
Uses
It finds its application as a masking agent, skin conditioning agent and soothing agent in cosmetics industry. The most important effects of Bisabolol for the use in cosmetics are anti-inflammatory, wound-healing, anti-bacterial and anti-mycotic. Bisabolol is therefore perfectly suited for the use in all kinds of skin-care products It can be used as active substance in cosmetic preparations for the protection and care of sensitive skin, preparations for babies and children, sunscreen and after-sun products, aftershaves and preparations for the oral hygiene.
Uses
alpha-Bisabolol is a botanical used for its anti-inflammatory and soothing properties. It is derived from chamomile and/or yarrow.
Preparation
Via Nerolidol plus glacial Acetic acid with Sulfuric acid to yield Bisabolol acetate, Saponification of that ester yields alpha-Bisabolol.
Definition
ChEBI: (+)-alpha-Bisabolol is a sesquiterpenoid.
Production Methods
rac-Bisabolol is produced by acid-catalyzed cyclization of farnesol or nerolidol. The individual enantiomers are obtained by extraction from the appropriate plants.
Safety Profile
Moderately toxic by ingestion.When heated to decomposition it emits acrid smoke andirritating vapors.
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