TRIMETHYLSILYL BROMOACETATE Chemical Properties

Boiling point:

57-58 °C/9 mmHg (lit.)

Density 

1.284 g/mL at 25 °C (lit.)

vapor density 

>1 (vs air)

refractive index 

n20/D 1.442(lit.)

Flash point:

83 °F

storage temp. 

Flammables area

form 

clear liquid

color 

Colorless to Light yellow

Specific Gravity

1.299

Hydrolytic Sensitivity

7: reacts slowly with moisture/water

Sensitive 

Moisture Sensitive

BRN 

1927560

CAS DataBase Reference

18291-80-0(CAS DataBase Reference)

Safety Information

Hazard Codes 

C

Risk Statements 

10-34

Safety Statements 

26-36/37/39-45

RIDADR 

UN 2920 8/PG 2

WGK Germany 

3

F 

10-19-21

TSCA 

No

HazardClass 

8

PackingGroup 

II

HS Code 

29310099

MSDS

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TRIMETHYLSILYL BROMOACETATE Usage And Synthesis

Chemical Properties

Clear slightly yellow liquid

Uses

Trimethylsilyl bromoacetate has been used:

• in the preparation of new imidazolium salts functionalized with the trimethylsilyl ester group
• as alkylating agent in the synthesis of succinate fragment of pantocin B (antibiotic natural product)
• in the synthesis of taxol derivatives tethered at C2′ and C-7 to glutamate and folate

TRIMETHYLSILYL BROMOACETATE(18291-80-0)Related Product Information

• TRIMETHYLSILYL(TRIMETHYLSILYL)PROPYNOATE
• TRIMETHYLSILYL CROTONATE
• trimethylsiloxytriethoxysilane
• TRIMETHYLSILYLBENZENESULFONATE
• BIS(TRIMETHYLSILYL) SULFATE
• TRIMETHYLSILYL(TRIMETHYLSILOXY)ACETATE
• TRIMETHYLOLPROPANE TRIS(3-MERCAPTOPROPIONATE)
• TRIMETHYLSILYL TRIFLUOROACETATE
• TRIMETHYLSILYL METHANESULFONATE
• ETHYL (METHYLTHIO)ACETATE
• Bromoacetic acid
• Silicon tetrahydride
• Acetic acid