Mal-PEG2-Val-Cit-amido-PAB-OH
Mal-PEG2-Val-Cit-amido-PAB-OH Basic information
- Product Name:
- Mal-PEG2-Val-Cit-amido-PAB-OH
- Synonyms:
-
- Mal-PEG2-Val-Cit-amido-PAB-OH
- Mal-PEG2-Val-Cit-PAB-OH
- L-Ornithinamide, N-[3-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-1-oxopropyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-
- CAS:
- 2055041-38-6
- MF:
- C29H42N6O9
- MW:
- 618.68
- Product Categories:
-
- ADC LINKER
- Mol File:
- 2055041-38-6.mol
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Mal-PEG2-Val-Cit-amido-PAB-OH Chemical Properties
- Boiling point:
- 948.4±65.0 °C(Predicted)
- Density
- 1.294±0.06 g/cm3(Predicted)
- solubility
- Soluble in DMSO, DMF
- pka
- 13.41±0.70(Predicted)
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Mal-PEG2-Val-Cit-amido-PAB-OH Usage And Synthesis
Description
Mal-PEG2-Val-Cit-PAB-OH is a cleavable ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. As this enzyme is only present in the lysosome, the ADC payload will be released only in the cell. The maleimide group is reactive toward thiol groups between pH 6.5 to 7.5. PEG chain increases the water solubility of the compound.
Mal-PEG2-Val-Cit-amido-PAB-OHSupplier
Beijing Jin Ming Biotechnology Co., Ltd.
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- 010-60605840 18892239720
- psaitong@jm-bio.com
Xi'an Confluore Biological Technology Co., Ltd.
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- +86-156-80926068 +86-15680926068
- 1924344760@qq.com
Abydos Scientific
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- 025-84767922 18936879710
- sales@abydoscientific.com
TargetMol Chemicals Inc.
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- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
Nanchang Tianzhen Biotechnology Co., Ltd
- Tel
- 13173652190
- pomy@tanzhenbio.com