Pacmilimab
Pacmilimab Basic information
- Product Name:
- Pacmilimab
- Synonyms:
-
- Pacmilimab
- Research Grade Pacmilimab(DHJ70105)
- Research Grade Pacmilimab
- Pacmilimab (anti-PD-L1)
- CAS:
- 2145091-51-4
- MW:
- 0
- Mol File:
- Mol File
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Pacmilimab Chemical Properties
- form
- Liquid
- color
- Colorless to light yellow
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Pacmilimab Usage And Synthesis
Uses
Pacmilimab (CX-072) is a potent PD-L1 inhibitor. Pacmilimab shows antitumor activity[1].
in vivo
Pacmilimab induces antitumor responses comparable to those of the same dose of the parental antibody in mice bearing MC38 tumors[1].
Pacmilimab accumulates in murine PD-L1-expressing tumors with minimal uptake in peripheral, non-cancerous lymphoid tissue, consistent with limited uptake in non-tumor PD-L1-expressing tissues and protection against autoimmunity[1].
References
[1] Naing A, et al. CX-072 (pacmilimab), a Probody ? PD-L1 inhibitor, in advanced or recurrent solid tumors (PROCLAIM-CX-072): an open-label dose-finding and first-in-human study. J Immunother Cancer. 2021 Jul;9(7):e002447. DOI:10.1136/jitc-2021-002447
PacmilimabSupplier
Shanghai YuanYe Biotechnology Co., Ltd.
- Tel
- 021-61312847; 18021002903
- 3008007409@qq.com
ShangHai Biochempartner Co.,Ltd
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- 177-54423994 17754423994
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Guangzhou Hongyuan Chemical Co.,Ltd
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- 15817493340
- 981810490@qq.com
Wuhan Chemstan Biotechnology Co., Ltd.
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- 027-65317797 15926423062
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TargetMol Chemicals Inc.
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- 4008200310
- marketing@tsbiochem.com