Basic information Safety Supplier Related

tert-Butyl rosuvastatin

Basic information Safety Supplier Related

tert-Butyl rosuvastatin Basic information

Product Name:
tert-Butyl rosuvastatin
Synonyms:
  • (3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[(methanesulfonyl)methylamino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid tert-butyl ester
  • tert-butyl rosuvastatin
  • tert-Butyl (6E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-enoate
  • (+)-(3R, 5S)-7-[4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-(N-METHYL-N-METHANESULFONYLAMINO)PYRIMIDIN-5-YL]-(3, 5)-DIHYDROXY-6(E)-HEPTENOATE
  • Rosuvastatin intermediate R-3
  • tert-Butyl(+)-(3R,5S)-7-[4-(4-Fluorophenyl)-6-Isopropyl-2-(N-Methyl-N-Methanesul fonylamino)pyrimidin-5-yl]-3,5-Dihydroxy-6(E)-Heptenoate
  • ZD-8
  • Tert-butyl-(+)7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N- methylsulfonylamino)pyrimidine-5-yl] -(3R,5S) -dihydroxy -(E)-6-Heptena
CAS:
355806-00-7
MF:
C26H36FN3O6S
MW:
537.64
EINECS:
609-144-4
Product Categories:
  • Rosuvastatin intermediates
  • Rosuvastatin Calcium and its intermediates
Mol File:
355806-00-7.mol
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tert-Butyl rosuvastatin Chemical Properties

Melting point:
136-138oC
Boiling point:
704.2±70.0 °C(Predicted)
Density 
1.259
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly, Heated)
form 
Solid
pka
13.38±0.20(Predicted)
color 
White to Off-White
Stability:
Hygroscopic
CAS DataBase Reference
355806-00-7(CAS DataBase Reference)
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tert-Butyl rosuvastatin Usage And Synthesis

Uses

Rosuvastatin tert-Butyl Ester, is a metabolite of Rosuvastatin (R700500) a selective, competitive HMG-CoA reductase inhibitor.

Uses

tert-Butyl Rosuvastatin is an impurity of Rosuvastatin (287714-41-4 #CAS), which is a HMG-?CoA reductase inhibitor. In combination of pemafibrate or a salt, it can function as cardiovascular disease medication.

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