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(3S,4S)-Tofacitinib

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(3S,4S)-Tofacitinib Basic information

Product Name:
(3S,4S)-Tofacitinib
Synonyms:
  • 3-((3S,4S)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
  • (3S,4S)-4-Methyl-3-(Methyl-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMino)-beta-oxo-1-piperidinepropanenitrile
  • (3S,4S)-Tofacitinib
  • 1-Piperidinepropanenitrile, 4-Methyl-3-(Methyl-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMino)-β-oxo-, (3S,4S)-
  • SS-tofacitinib
  • Tofacitinib IMpurity A
  • Tofacitinib IMpurity C Citrate
  • Tofacitinib Impurity C(3S,4S)
CAS:
1092578-47-6
MF:
C16H20N6O
MW:
312.37
Mol File:
Mol File
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(3S,4S)-Tofacitinib Chemical Properties

Density 
1.296
storage temp. 
Store at -20°C
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
6.04±0.60(Predicted)
form 
Powder
color 
Off-white to pink
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(3S,4S)-Tofacitinib Usage And Synthesis

Uses

(3S,4S)-Tofacitinib is an enantiopure stereoisomer of the drug, Janus kinase 3(Jak3) inhibitor(CP-690,550).

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