Benzamide, 4-[2-[1,5-dihydro-1-(4-nitrophenyl)-5-oxo-3-phenyl-4H-pyrazol-4-ylidene]hydrazinyl]- Chemical Properties

Boiling point:

657.7±65.0 °C(Predicted)

Density 

1.45±0.1 g/cm3(Predicted)

pka

8.33±0.40(Predicted)

Benzamide, 4-[2-[1,5-dihydro-1-(4-nitrophenyl)-5-oxo-3-phenyl-4H-pyrazol-4-ylidene]hydrazinyl]- Usage And Synthesis

Description

ZINC04177596 is a novel Nef Protein Inhibitor; Anti-HIV.

Uses

ZINC04177596 is a potent HIV-negative factor (HIV-Nef) protein inhibitor. Nef is an accessory gene product of HIV and has an imperative role in viral replication and AIDS pathogenesis[1].

References

[1] Moonsamy S, et al. Identification of Binding Mode and Prospective Structural Features of Novel Nef Protein Inhibitors as Potential Anti-HIV Drugs. Cell Biochem Biophys. 2017;75(1):49-64. DOI:10.1007/s12013-016-0774-1

Benzamide, 4-[2-[1,5-dihydro-1-(4-nitrophenyl)-5-oxo-3-phenyl-4H-pyrazol-4-ylidene]hydrazinyl]-(364052-84-6)Related Product Information

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