N-(2-(1H-indol-3-yl)ethyl)-2-((8-oxo-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-12-yl)oxy)propanamide Chemical Properties

Boiling point:

800.5±65.0 °C(Predicted)

Density 

1.40±0.1 g/cm3(Predicted)

pka

14.77±0.46(Predicted)

N-(2-(1H-indol-3-yl)ethyl)-2-((8-oxo-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-12-yl)oxy)propanamide Usage And Synthesis

Description

ZINC08792355 is a novel SIRT1 inhibitor.

Uses

ZINC08792355 is a SIRT1 inhibitor and can be used for study of ageing, diabetes, and cancer.[1].

References

[1] Sun Y, et al. Ligand-based virtual screening and inductive learning for identification of SIRT1 inhibitors in natural products. Sci Rep. 2016;6:19312. Published 2016 Jan 25. DOI:10.1038/srep19312

N-(2-(1H-indol-3-yl)ethyl)-2-((8-oxo-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-12-yl)oxy)propanamide(904513-52-6)Related Product Information

• ZINC13466751
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• 3-Thiophenecarboxylic acid, 5-[[4-(carboxymethoxy)-3-methoxyphenyl]methylene]-2-[(4-ethoxyphenyl)amino]-4,5-dihydro-4-oxo-, 3-ethyl ester
• (5Z)-2-hydroxy-4-methyl-6-oxo-5-[(5-phenylfuran-2-yl)methylidene]-5,6-dihydropyridine-3-carbonitrile
• Benzamide, 4-[2-[1,5-dihydro-1-(4-nitrophenyl)-5-oxo-3-phenyl-4H-pyrazol-4-ylidene]hydrazinyl]-
• N-(2-(1H-indol-3-yl)ethyl)-2-((8-oxo-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-12-yl)oxy)acetamide
• ZINC03129319
• 6-[(phenylsulfanyl)methyl]-2-sulfanylpyrimidin-4-ol