3,4,5-Trimethoxyaniline Chemical Properties

Melting point:

110-113 °C (lit.)

Boiling point:

316.88°C (rough estimate)

Density 

1.1967 (rough estimate)

refractive index 

1.4760 (estimate)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

pka

4.35±0.10(Predicted)

form 

Powder

color 

Off-white to beige-brown, gray, or pink

BRN 

642919

InChIKey

XEFRNCLPPFDWAC-UHFFFAOYSA-N

CAS DataBase Reference

24313-88-0(CAS DataBase Reference)

EPA Substance Registry System

3,4,5-Trimethoxyaniline (24313-88-0)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

37/38-36/37/38-20/21/22

Safety Statements 

22-24/25-37/39-26-24-36

RIDADR 

2811

WGK Germany 

3

Hazard Note 

Harmful

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

III

HS Code 

29222900

MSDS

• Language:English Provider:3,4,5-Trimethoxyaniline
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

3,4,5-Trimethoxyaniline Usage And Synthesis

Chemical Properties

3,4,5-Trimethoxyaniline is off-white to beige-brown, grey or pink powder

Uses

3,4,5-Trimethoxyaniline is a tri-substituted aniline derivative with sympatholytic activity. It is used in the preparation of a novel class of anticancer agents.

Application

3,4,5-Trimethoxyaniline can be used:
(1) As experimental studies, infrared spectra and laser Raman spectra of 3,4,5-trimethoxyaniline were investigated^[1].
(2) Tropanilisation, detropanilisation and Schiff base formation in the reaction of 3,4,5-trimethoxyaniline with tropanilide ions as organic reaction reagents^[2].

Application

[1] BANDANA SHARMA; Shweta P; Munish Kumar Yadav. MOLECULAR STRUCTURE, EXPERIMENTAL AND THEORETICAL (HF, DFT) SPECTRAL ANALYSIS OF 3,4,5- TRIMETHOXYANILINE[J]. Rasayan Journal of Chemistry, 2023. DOI:10.31788/rjc.2023.1628371.
[2] J. TSUNETSUGU; S. E; M SATO. ChemInform Abstract: TROPENYLATION, DETROPENYLATION AND SCHIFF BASE FORMATION IN THE REACTION OF 3,4,5-TRIMETHOXYANILINE WITH TROPENYLIUM ION[J]. ChemInform, 1975. DOI:10.1002/chin.197545221.

3,4,5-Trimethoxyaniline(24313-88-0)Related Product Information

• Trimethyl phosphite
• 4-(Trifluoromethoxy)aniline
• (Trifluoromethoxy)benzene
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• m-Anisidine
• p-Anisidine
• o-Anisidine
• 3,4,5-TRIMETHOXYPHENYL ISOTHIOCYANATE
• 1-(3,4,5-TRIMETHOXYPHENYL)-2-THIOUREA
• 3,4,5-TRIMETHOXYPHENYL ISOCYANATE
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• N-METHYL-3,4,5-TRIMETHOXYBENZYLAMINE
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• 1,2,3-TRIMETHOXY-5-NITROBENZENE
• 3,4,5-TRIMETHOXY-ACETOACETANILIDE
• 2-CHLORO-N-(3,4,5-TRIMETHOXYPHENYL)ACETAMIDE
• ASISCHEM C66342
• 4-(3,4,5-TRIMETHOXYPHENYL)-3-THIOSEMICARBAZIDE