2,4,6-Trichlorobenzoyl chloride Chemical Properties

Melting point:

165-166 °C

Boiling point:

107-108 °C/6 mmHg (lit.)

Density 

1.561 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.5754(lit.)

Flash point:

>230 °F

storage temp. 

Sealed in dry,Room Temperature

solubility 

Acetonitrile (Slightly), Chloroform (Sparingly), Ethyl Acetate (Slightly)

form 

Liquid

Specific Gravity

1.561

color 

Clear yellow

Water Solubility 

Reacts with water.

Sensitive 

Moisture Sensitive

BRN 

2050280

InChIKey

OZGSEIVTQLXWRO-UHFFFAOYSA-N

CAS DataBase Reference

4136-95-2(CAS DataBase Reference)

Safety Information

Hazard Codes 

C

Risk Statements 

34

Safety Statements 

26-27-28-36/37/39-45-25

RIDADR 

UN 3265 8/PG 2

WGK Germany 

3

HazardClass 

8

PackingGroup 

II

HS Code 

29163990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

2,4,6-Trichlorobenzoyl chloride Usage And Synthesis

Description

2,4,6-Trichlorobenzoyl chloride is a chemical compound that forms during the synthesis of benzalkonium chloride. It can be used as an efficient method for the synthesis of fatty acids and cyclic peptides. The reaction products are chlorinated and have a hydroxyl group. It is used in the synthesis of fatty acids by reacting with acetic acid to produce a chlorinated fatty acid. Hydroxyl groups react with 2,4,6-trichlorobenzoyl chloride to form a chlorinated hydroxy fatty acid.

Chemical Properties

clear yellow liquid

Uses

2,4,6-Trichlorobenzoyl chloride may be used in the preparation of:

• γ-lactone and δ-lactone
• aliphatic aromatic anhydrides, required for the synthesis of amphiphilic hyaluronan
• mixed anhydride, required for the synthesis of angelate esters
• synthesis of both spongistatin 1 and spongistatin 2
• large-ring lactones in high yields.

Application

2,4,6-Trichlorobenzoyl chloride has been shown to inhibit cervical cancer cell growth and reduce the incidence of cervical cancer by inhibiting DNA replication.

2,4,6-Trichlorobenzoyl chloride(4136-95-2)Related Product Information

• Choline chloride
• Calcium chloride
• 2,3-Dichlorobenzoyl chloride
• Oxalyl chloride
• Ammonium chloride
• 2-Chlorobenzoyl chloride
• Sodium chloride
• Sucralose
• p-Toluoyl chloride
• 4-Chlorobenzoyl chloride
• 2,4-Dichlorobenzoyl chloride
• Zinc chloride
• 2-Fluorobenzoyl chloride
• 3,5-Dichlorobenzoyl chloride
• Thionyl chloride
• Potassium chloride
• 3-Methylbenzoyl chloride
• Benzoyl chloride