13-Deoxocarminomycin
13-Deoxocarminomycin Basic information
- Product Name:
- 13-Deoxocarminomycin
- Synonyms:
-
- 13-Deoxocarminomycin
- 13-deoxycarminomycin
- (8S)-10α-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-ethyl-7,8,9,10-tetrahydro-1,6,8α,11-tetrahydroxy-5,12-naphthacenedione
- 13-Deoxocarminomycin I
- D-788-11
- R-20X
- Daunorubicin Impurity 4
- Antibiotic D 788-11
- CAS:
- 76034-18-9
- MF:
- C26H29NO9
- MW:
- 499.513
- Mol File:
- 76034-18-9.mol
13-Deoxocarminomycin Chemical Properties
- Boiling point:
- 713.1±60.0 °C(Predicted)
- Density
- 1.57±0.1 g/cm3(Predicted)
- solubility
- Chloroform (Slightly), DMSO (Slightly)
- form
- Solid
- pka
- 6.48±0.60(Predicted)
- color
- Very Dark Green to Black
- Stability:
- Light Sensitive
13-Deoxocarminomycin Usage And Synthesis
Uses
13-Deoxycarminomycin is used as antitumor agents in preparation of 3''-Deamino-3''-(2"-pyrroline-1"-yl)-5-imine-13-deoxyanthracyclines. 13-Deoxycarminomycin is a doxA gene confers on the transformed host the ability to convert Daunomycin and 13-Dihydrodaunomycin to Doxorubicin.
Definition
ChEBI: 13-deoxycarminomycin is a cytotoxic anthracycline antibiotic that is produced by Streptomyces peucetius var. carminatus (a biochemical mutant of Streptomyces peucetius var. caesius), and is active against P-388 murine leukemia. It has a role as an antineoplastic agent and a bacterial metabolite. It is an anthracycline antibiotic, an aminoglycoside antibiotic, a member of p-quinones, a member of tetracenequinones and a tertiary alcohol. It is a conjugate base of a 13-deoxycarminomycin(1+). It derives from a hydride of a tetracene.
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