L-Tyrosine Ethyl Ester Hydrochloride
L-Tyrosine Ethyl Ester Hydrochloride Basic information
- Product Name:
- L-Tyrosine Ethyl Ester Hydrochloride
- Synonyms:
-
- (S)-2-AMINO-3-(4-HYDROXY-PHENYL)-PROPIONIC ACID ETHYL ESTER HCL
- TEE
- ethylester,hydrochloride,l-tyrosin
- tyrosineethylesterhydrochloride
- TYROSINE-OET HCL
- Tyr-Oet Hcl
- L-TYROSINE ETHYL ESTER MONOHYDROCHLORIDE
- L-TYROSINE ETHYL ESTER HYDROCHLORIDE SALT
- CAS:
- 4089-07-0
- MF:
- C11H16ClNO3
- MW:
- 245.7
- EINECS:
- 223-820-2
- Product Categories:
-
- Amino Acids
- I - ZPeptide Synthesis
- Modified Amino Acids
- Tyrosine [Tyr, Y]
- Amino Acids and Derivatives
- Amino Acid Derivatives
- Amino Acids
- Amino hydrochloride
- Biochemistry
- Amino Acids (C-Protected)
- Amino Acid Ethyl Esters
- Tyrosine
- Peptide Synthesis
- Mol File:
- 4089-07-0.mol
L-Tyrosine Ethyl Ester Hydrochloride Chemical Properties
- Melting point:
- 166-170 °C
- alpha
- [α]D20 +26～+30° (c=5, C2H5OH)
- refractive index
- -6.5 ° (C=2, H2O)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- powder to crystal
- color
- White to Almost white
- Water Solubility
- Soluble in water (3.685e+005 mg/L @ 25°C (est.)).
- BRN
- 4725904
- InChIKey
- BQULAXAVRFIAHN-PPHPATTJSA-N
- LogP
- 1.060 (est)
- CAS DataBase Reference
- 4089-07-0(CAS DataBase Reference)
Safety Information
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 22-24/25-37/39-26
- WGK Germany
- 2
- RTECS
- YP2580000
- HS Code
- 29225090
MSDS
- Language:English Provider:Ethyl L-tyrosinate hydrochloride
- Language:English Provider:SigmaAldrich
- Language:English Provider:ACROS
- Language:English Provider:ALFA
L-Tyrosine Ethyl Ester Hydrochloride Usage And Synthesis
Chemical Properties
White to off-white microcrystalline powder
Uses
L-Tyrosine Ethyl Ester Hydrochloride is used as a medical and organic intermediate and as an important amino protective agent. It is also used to introduce t-Boc protect gene.
Application
Papain is also used for synthesizing poly(L-tyrosine) and poly(L-glutamic acid) using L-tyrosine ethyl ester hydrochloride and L-glutamic acid diethyl ester hydrochloride as the substrates, respectively. The protease-catalyzed copolymerization of amino acids is first achieved by papain using L-glutamic acid ester and various amino acid esters as substrates.
A mixture of L-tyrosine ethyl ester hydrochloride, the appropriate acid anhydri-des, triethylamine and dry tetrahydrofuran, was warmed for an hour in an atmosphere of nitrogen. After removing the amine salt, Ic and Id became crystalline on standing overnight in the cold.
Preparation
synthesis of L-Tyrosine Ethyl Ester Hydrochloride: Esterification of 25 g. ol L-tyrosine (0.014 mole) with ethanolic hydrogen chloride gave 24.1 g. of L-tyrosine ethyl ester hydrochloride (80%). Liberation of the ester by slurrying the hydrochloride in chloroform rollowed by the addition of chloroform saturated with ammonia, removal of the ammonium chloride by filtration and evaporation of the chloroform gave 19.4 g. of L-tyrosine ethyl ester (67%), m.p. 106-108 ° .
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L-Tyrosine Ethyl Ester Hydrochloride(4089-07-0)Related Product Information
- Ethyl 3-aminopropanoate hydrochloride
- Ethanol
- Ethyl acrylate
- Methyl L-tyrosinate hydrochloride
- Tris(trimethylsilyl)phosphate
- L-Tyrosine
- Ethyl formate
- Ethyl cyanoacetate
- Boc-D-Tyr-OH
- Topotecan hydrochloride
- H-ARG-ARG-LEU-ILE-GLU-ASP-ASN-GLU-TYR-THR-ALA-ARG-GLY-OH
- Ethylparaben
- TYROSINASE
- ISOXADIFEN-ETHYL
- L-Tyrosine hydrochloride
- Ethyl L-tyrosinate
- Glycine ethyl ester hydrochloride
- Ethyl acetate