1,4-BIS-MALEIMIDOBUTANE
1,4-BIS-MALEIMIDOBUTANE Basic information
- Product Name:
- 1,4-BIS-MALEIMIDOBUTANE
- Synonyms:
-
- N,N'-(1,4-Butanediyl)di(maleimide)
- N,N'-Tetramethylenebis(maleimide)
- 1-(4-maleimidobutyl)-3-pyrroline-2,5-quinone
- 1-[4-(2,5-dioxopyrrol-1-yl)butyl]pyrrole-2,5-dione
- TetraMethylenebisMaleiMide
- TetraMethylenediMaleiMide
- 1H-Pyrrole-2,5-dione, 1,1'-(1,4-butanediyl)bis-
- 1,4-Bis-MaleiMidobutane(BMB)
- CAS:
- 28537-70-4
- MF:
- C12H12N2O4
- MW:
- 248.23
- Product Categories:
-
- Homobifunctional Crosslinker
- pharmacetical
- Maleimide Derivatives
- Cross Linking Reagents
- MTS & Sulfhydryl Active Reagents
- Mol File:
- 28537-70-4.mol
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1,4-BIS-MALEIMIDOBUTANE Chemical Properties
- Melting point:
- 196-197°C
- Boiling point:
- 450.3±28.0 °C(Predicted)
- Density
- 1.388±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- solubility
- Chloroform
- form
- Solid
- pka
- -1.93±0.20(Predicted)
- color
- White to Off-White
- Appearance
- White solid
- BRN
- 1538100
- InChI
- InChI=1S/C12H12N2O4/c15-9-3-4-10(16)13(9)7-1-2-8-14-11(17)5-6-12(14)18/h3-6H,1-2,7-8H2
- InChIKey
- WXXSHAKLDCERGU-UHFFFAOYSA-N
- SMILES
- C(N1C(=O)C=CC1=O)CCCN1C(=O)C=CC1=O
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MSDS
- Language:English Provider:SigmaAldrich
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1,4-BIS-MALEIMIDOBUTANE Usage And Synthesis
Chemical Properties
Off-White Powder
Uses
A short, sulfhydryl reactive homobifunctional crosslinking reagent
Synthesis
1449655-98-4
28537-70-4
General method: 1,4-bis(bromomethyl)benzene (1 mol) was dissolved in 1,1,2,2-tetrachloroethane in an open-ended flask with continuous stirring at 120°C for 12 hours. The reaction process was monitored by thin layer chromatography (TLC). When the reaction was complete, the solvent was removed by evaporation under reduced pressure to give 1,4-bis(maleimido)butane (BMI).
References
[1] Tetrahedron Letters, 2013, vol. 54, # 37, p. 5011 - 5013
1,4-BIS-MALEIMIDOBUTANESupplier
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