jolkinolide A
jolkinolide A Basic information
- Product Name:
- jolkinolide A
- Synonyms:
-
- jolkinolide A
- (4aR,6aS,7aβ)-2,3,4,4aα,5,6,11aα,11b-Octahydro-4,4,8,11bβ-tetramethyl-1H-oxireno[1,10a]phenanthro[3,2-b]furan-9(7aH)-one
- (5β,9β,10α)-8β,14β:12,16-Diepoxyabieta-11,13(15)-dien-16-one
- 1H-Oxireno[1,10a]phenanthro[3,2-b]furan-9(7aH)-one, 2,3,4,4a,5,6,11a,11b-octahydro-4,4,8,11b-tetramethyl-, (4aR,6aS,7aR,11aS,11bR)-
- CAS:
- 37905-07-0
- MF:
- C20H26O3
- MW:
- 314.42
- Mol File:
- 37905-07-0.mol
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jolkinolide A Chemical Properties
- Boiling point:
- 479.5±45.0 °C(Predicted)
- Density
- 1.19±0.1 g/cm3(Predicted)
- InChI
- InChI=1S/C20H26O3/c1-11-15-12(22-17(11)21)10-14-19(4)8-5-7-18(2,3)13(19)6-9-20(14)16(15)23-20/h10,13-14,16H,5-9H2,1-4H3/t13-,14+,16-,19-,20+/m1/s1
- InChIKey
- OYXDHOVYZKWSRM-PHJMNMFVSA-N
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jolkinolide A Usage And Synthesis
Uses
Jolkinolide A can be used as a bone marrow mesenchymal stem cell osteogenic differentiation accelerator. It can be developed using matrix solid-phase dispersion coupled with high-performance liquid chromatography.
Definition
ChEBI: A natural product found in Euphorbia fischeriana.
in vivo
Jolkinolide A (40 mg/kg; i.p.; once every 3 days, for 2 months) inhibits the expression of the VEGF protein in A549 cell xenograft tumor model in mouse[1].
| Animal Model: | Female BALB/c nude mice (4-5 weeks old) injected with A549 cells[1] |
| Dosage: | 40 mg/kg |
| Administration: | Intraperitoneal injection; once every 3 days for 2 months |
| Result: | Significantly inhibited the expression of VEGF protein on the first, 10th, 30th, 45th, and 60th day of administration. |
jolkinolide ASupplier
Nanjing Dasf Biotechnology Co., Ltd. Gold
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- 025-025-+86-02585846866 +86-18094231287
- 1773155960@qq.com
BioBioPha Co., Ltd.
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- 0871-65217109 13211707573;
- y.liu@mail.biobiopha.com
Wuhan ChemFaces Biochemical Co., Ltd.
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- 18607101326 15172504745
- aileen@chemfaces.com
EMMX Biotechnology LLC
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- 888-539-0666
- info@emmx.com
Shanghai YuanYe Biotechnology Co., Ltd.
- Tel
- 021-61312847; 18021002903
- 3008007409@qq.com