pectolinarin Chemical Properties

Melting point:

>250°C (dec.)

Boiling point:

896.4±65.0 °C(Predicted)

Density 

1.61±0.1 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

DMSO (Slightly, Heated), Pyridine (Slightly)

form 

Solid

pka

6.09±0.40(Predicted)

color 

Off-White to Pale Yellow

InChIKey

DUXQKCCELUKXOE-OXBSKWRUNA-N

Safety Information

HS Code 

29389090

pectolinarin Usage And Synthesis

Chemical Properties

Yellow powder

Uses

antiinflammatory, analgesic

Uses

Pectolinarin is obtained from Linaria reflexa, and is a flavonoid displaying antioxidant activity in vitro.

Definition

ChEBI: Pectolinarin is a disaccharide derivative that consists of pectolinarigenin substituted by a 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. It has a role as an apoptosis inducer, an anti-inflammatory agent, a plant metabolite, an antineoplastic agent, an EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor and an antioxidant. It is a dimethoxyflavone, a rutinoside, a glycosyloxyflavone, a disaccharide derivative and a monohydroxyflavanone. It is functionally related to a pectolinarigenin.

Biological Activity

Pectolinarinexerts anti-inflammatory, antioxidant, antidiabetic, and antitumor activities. It is known to be a potent agent for the treatment of neurodegenerative disorders. It also displays antiviral, and antiparasitic effects and can inhibit bacterial biofilm formation. Pectolinarin relieves lipopolysaccharide-induced liver and kidney injuries.

target

COX | NF-kB | PGE

pectolinarin(28978-02-1)Related Product Information

• (3S,4S,5S,6S)-2-(methoxycarbonyl)-6-(p-tolylthio)tetrahydro-2H-pyran-3,4,5-triyl tris(2-methylpropanoate)
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• hydroxygenkwanin
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• 4',5-DIHYDROXY-7-METHOXYFLAVONE