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furomollugin

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furomollugin Basic information

Product Name:
furomollugin
Synonyms:
  • furomollugin
  • 5-Hydroxynaphtho[1,2-b]furan-4-carboxylic acid methyl ester
  • Naphtho[1,2-b]furan-4-carboxylic acid, 5-hydroxy-, methyl ester
CAS:
61658-41-1
MF:
C14H10O4
MW:
242.23
Mol File:
61658-41-1.mol
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furomollugin Chemical Properties

Melting point:
42 °C
Boiling point:
391.6±22.0 °C(Predicted)
Density 
1.370±0.06 g/cm3(Predicted)
pka
8.89±0.30(Predicted)
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furomollugin Usage And Synthesis

Uses

Furomollugin is a natural product with antioxidant and antibacterial activities, can be isolated from Rubia cordifolia. Furomollugin lacks potent anti-tyrosinase activity, but also exhibits significant anticancer property[1].

References

[1] Xia L, et al. Anti-tyrosinase, antioxidant, and antibacterial activities of novel 5-hydroxy-4-acetyl-2,3-dihydronaphtho[1,2-b]furans. Eur J Med Chem. 2014 Oct 30;86:605-12. DOI:10.1016/j.ejmech.2014.09.025
[2] Xia L, et al. Antioxidant and antibacterial evaluation of synthetic furomollugin and its diverse analogs[J]. Medicinal Chemistry Research, 2014, 23(7): 3528-3538.

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