cynaropicrin
cynaropicrin Basic information
- Product Name:
- cynaropicrin
- Synonyms:
-
- 2-Hydroxymethylpropenoic acid (3aR,4S,6aβ,9aβ,9bα)-dodecahydro-8α-hydroxy-3,6,9-tris(methylene)-2-oxoazuleno[4,5-b]furan-4-yl ester
- Cynaropikrin
- [(3aR,4S,6aR,8S,9aR,9bR)-8-hydroxy-3,6,9-trimethylidene-2-oxo-3a,4,5,6a,7,8,9a,9b-octahydroazuleno[4,5-b]furan-4-yl] 2-(hydroxymethyl)prop-2-enoate
- 2-methylolacrylic acid [(3aR,4S,6aR,8S,9aR,9bR)-8-hydroxy-2-keto-3,6,9-trimethylene-3a,4,5,6a,7,8,9a,9b-octahydroazuleno[4,5-b]furan-4-yl] ester
- CYNAROPICRIN(SH)
- cynaropicrin
- Cynaropicrin - Cynara cardunculus (artichoke)
- 2-Propenoic acid, 2-(hydroxymethyl)-, (3aR,4S,6aR,8S,9aR,9bR)-dodecahydro-8-hydroxy-3,6,9-tris(methylene)-2-oxoazuleno[4,5-b]furan-4-yl ester
- CAS:
- 35730-78-0
- MF:
- C19H22O6
- MW:
- 346.37
- Mol File:
- 35730-78-0.mol
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cynaropicrin Chemical Properties
- Boiling point:
- 566.2±50.0 °C(Predicted)
- Density
- 1.28±0.1 g/cm3 (20 ºC 760 Torr)
- storage temp.
- -20°C, protect from light
- solubility
- DMSO:50.0(Max Conc. mg/mL);144.35(Max Conc. mM)
- pka
- 13.52±0.10(Predicted)
- LogP
- 1.340 (est)
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cynaropicrin Usage And Synthesis
Uses
Cynaropicrin can inhibit lipopolysaccharide-induced TNF-α release from either murine or human macrophage cells in a dose-dependent manner with the IC50 values of 8.24 and 3.18 μM, respectively. It can also inhibit the increase of cartilage degradation factor (MMP13) and suppresses NF-κB signaling.
Definition
ChEBI: Cynaropicrin is a sesquiterpene lactone.
cynaropicrinSupplier
Chengdu Biopurify Phytochemicals Ltd.
- Tel
- +86-028-82633397 18982077548
- cwb1@biopurify.cn
Shanghai Winherb Medical Technology Co., Ltd.
- Tel
- 400-1865138 13341702378
- 190129269@qq.com
Shanghai Tauto Biotech Co., Ltd.
- Tel
- 021-51320588
- tauto@tautobiotech.com
Wuhan ChemFaces Biochemical Co., Ltd.
- Tel
- 18607101326 15172504745
- aileen@chemfaces.com
EMMX Biotechnology LLC
- Tel
- 888-539-0666
- info@emmx.com
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