liriodenine
liriodenine Basic information
- Product Name:
- liriodenine
- Synonyms:
-
- Iiriodenine
- liriodenine
- 8H-Benzo[G]-1,3-benzodioxolo[6,5,4-de]quinolin-8-one
- Micheline b
- Noraporphin-7-one, 4,5,6,6A-tetradehydro-1,2-(methylenedioxy)-
- Nsc93681
- Oxoushinsunin
- Oxoushinsunine
- CAS:
- 475-75-2
- MF:
- C17H9NO3
- MW:
- 275.26
- Mol File:
- 475-75-2.mol
liriodenine Chemical Properties
- Melting point:
- 282°C
- Boiling point:
- 531.0±19.0 °C(Predicted)
- Density
- 1.501±0.06 g/cm3(Predicted)
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- powder
- pka
- 2.67±0.20(Predicted)
- color
- Yellow
liriodenine Usage And Synthesis
Description
Isolated from the heartwood extract of Liriodendron tulip/era, this base may be purified by crystallization from CHCI3. It contains one methylenedioxy group and a keto group, forming a crystalline oxime, m.p. 271°C. The structure has been confirmed by synthesis, the synthetic alkaloid having a higher melting point of 287°C.
Uses
Liriodenine is an isoquinoline alkaloid found in extracts of medicinal Asian vegetation such as Michelia alba and Liriodendron chinense.
Definition
ChEBI: An oxoaporphine alkaloid that is 4,5,6,6a-tetradehydronoraporphin-7-one substituted by a methylenedioxy group across positions 1 and 2. It is isolated from Annona glabra and has been shown to exhibit antimicrobial and cytotoxic activities.
target
p53 | Caspase | Bcl-2/Bax | Sodium Channel | Potassium Channel | Topoisomerase | cAMP
References
Buchanan, Dickey.,J. Org. Chern., 25, 1389 (1960)
Taylor., Tetrahedron, 14,42 (1961)
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liriodenine(475-75-2)Related Product Information
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- alpha-Cyperone
- Hydroxyecdysone
- hydroxygenkwanin
- alpha-Terpineol
- Artemether
- 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one
- (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one
- beta-Sitosterol
- ISOQUINOLINE-1-CARBALDEHYDE
- 1-ISOQUINOLINYL PHENYL KETONE
- 8-METHYL-ISOQUINOLINE
- Liriodenine methiodide
- liriodenine
- 1-ISOQUINOLIN-1-YL-ETHANONE
- 1-Benzylisoquinoline
- 2-(2-METHYLBENZOYL)PYRIDINE
- [1,3]DIOXOLO[4,5-G]ISOQUINOLINE