3,3'-DIHEXYLOXACARBOCYANINE IODIDE Chemical Properties

Melting point:

219-221 °C(lit.)

Density 

1.2837 (estimate)

storage temp. 

room temp

solubility 

Soluble in ethanol, methanol, dimethyl sulfoxide

form 

Powder

color 

Red

Appearance

Orange yellow solid

ex/em

484/501 nm (MeOH)

ε(extinction coefficient)

≥120000 at 483-488nm in methanol at 0.01g/L

Sensitive 

Light Sensitive

λmax

484 nm

BRN 

9312562

Biological Applications

Detecting mitochondrial membrane potential,3,10–16,47,nucleic acid hybridization,prostate cancer,germination Bacillus anthracis spores; apoptosis assays; diagnostic assays; in photodynamic therapy; treating malaria,leishmaniasis,t

CAS DataBase Reference

53213-82-4(CAS DataBase Reference)

EPA Substance Registry System

Benzoxazolium, 3-hexyl-2-[3-(3-hexyl-2(3H)-benzoxazolylidene)-1-propenyl]-, iodide (53213-82-4)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

RTECS 

DM5285250

F 

8

TSCA 

Yes

HS Code 

29269095

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

3,3'-DIHEXYLOXACARBOCYANINE IODIDE Usage And Synthesis

Description

3,3'-Dihexyloxacarbocyanine is a cell-permeable green fluorescent dye that is used as a membrane potential probe. At high concentrations, 3,3'-Dihexyloxacarbocyanine accumulates in the endoplasmic reticulum (ER) and has been used to visualize ER in moss, yeast, and muscle cells. At low concentrations, it accumulates in mitochondria and has been used to assess mitochondrial dislocations, fusion, and fission in living cells, as well as to visualize cellular apoptosis.

Chemical Properties

RED CRYSTALLINE POWDER

Uses

Endoplasmic Reticulum-Tracker dye is a cell-permeant, live-cell stain that is highly selective for the ER. This dye rarely stain mitochondria, unlike the conventional ER stain DiOC6(3) and staining at low concentrations does not appear to be toxic to cell

Excitation / Emission Maximum

484 nm/501 nm

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