4-Methylbenzamide oxime Chemical Properties

Melting point:

140-145 °C (lit.)

Boiling point:

258.1±33.0 °C(Predicted)

Density 

1.14±0.1 g/cm3(Predicted)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 0.5 mg/ml

form 

A crystalline solid

pka

6.95±0.69(Predicted)

CAS DataBase Reference

19227-13-5(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

RTECS 

XS4870000

HazardClass 

IRRITANT

HS Code 

2928009090

MSDS

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4-Methylbenzamide oxime Usage And Synthesis

Description

4-Methylbenzamide oxime is intended to be used as a building block in drug discovery chemistry.

Uses

N-Hydroxy-4-methyl-benzenecarboximidamide is a reactant used in the preparation of naphthyridine-based polycyclic hetarenes from N-hydroxybenzamidines and alkynes.

General Description

4-Methylbenzamide oxime is a benzonitrile derivative that can be prepared from 4-methylbenzonitrile and hydroxylamine hydrochloride. Its crystalline structure shows the presence of both intramolecular and intermolecular hydrogen bonds. 3-Aryl-5-trinitromethyl-1,2,4-oxadiazoles undergoes hydrolysis under acidic conditions to form 4-methylbenzamide oxime as one of the product.

4-Methylbenzamide oxime(19227-13-5)Related Product Information

• p-Toluic acid
• p-Toluoyl chloride
• Isopropyl-α-[2-methylhydrazino]-p-toluamide
• 2-(Trifluoromethyl)benzyl chloride
• 3-Methylbenzoyl chloride
• Phenethyl alcohol
• Benzamide
• BENZAMIDINE
• p-Tolunitrile
• 4-Methylbenzyl chloride
• 2-CHLOROTHIOPHENOL
• Chlorantraniliprole
• CHLOROPHOSPHONAZO III
• N-Methyl-2-pyrrolidone
• Benzylparaben
• 2-Cyanophenol
• 4-TERT-BUTYLBENZAMIDOXIME
• CARBOXY-PTIO