Heptaethylene glycol di(p-toluenesulfonate)
Heptaethylene glycol di(p-toluenesulfonate) Basic information
- Product Name:
- Heptaethylene glycol di(p-toluenesulfonate)
- Synonyms:
-
- Heptaethylene glycol di(p-toluenesulfonate)
- Tos-PEG8-Tos
- 3,6,9,12,15,18-Hexaoxaicosane-1,20-diyl bis(4-methylbenzenesulfonate)
- Bis-Tos-PEG7
- 3,6,9,12,15,18-Hexaoxaeicosane-1,20-diol, 1,20-bis(4-methylbenzenesulfonate)
- Inhibitor,inhibit,Bis-Tos-PEG-7,Bis Tos PEG7,BisTosPEG7,PROTAC Linkers
- Tos-PEG7-Tos/3,6,9,12,15,18-Hexaoxaeicosane-1,20-diol, 1,20-bis(4-methylbenzenesulfonate)
- 20-[(4-methylbenzenesulfonyl)oxy]-3,6,9,12,15,18-hexaoxaicosan-1-yl 4-methylbenzene-1-sulfonate
- CAS:
- 69502-27-8
- MF:
- C28H42O12S2
- MW:
- 634.75588
- Mol File:
- 69502-27-8.mol
More
Less
Heptaethylene glycol di(p-toluenesulfonate) Chemical Properties
- form
- Liquid
- color
- Colorless to light yellow
More
Less
Heptaethylene glycol di(p-toluenesulfonate) Usage And Synthesis
Description
Tos-PEG8-Tos is a PEG linker containing two tosyl groups. The hydrophilic PEG spacer increases solubility in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions.
Uses
Bis-Tos-PEG7 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Heptaethylene glycol di(p-toluenesulfonate)Supplier
Nanjing Junnahe Biopharmaceutical Co., Ltd
- Tel
- 025-58367986 17351780683
- amy.xiang@ally-chem.com
Shanghai Raise Chemical Technology Co.,Ltd
- Tel
- 15026594951
- rs@raise-chem.com
Jinan elephant international trading co., LTD
- Tel
- 13006575422@163.com
Amadis Chemical Company Limited
- Tel
- 571-89925085
- sales@amadischem.com
Hubei Xinyuanshun Pharmaceutical Chemical Co., Ltd.
- Tel
- 027-50664929, 13971561712
- hubxys2001@163.com