4-Acetyl-4'-bromobiphenyl Chemical Properties

Melting point:

129-133 °C(lit.)

Boiling point:

372.1±17.0 °C(Predicted)

Density 

1.359±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

solubility 

soluble in Toluene

form 

powder to crystal

color 

White to Orange to Green

BRN 

2048590

InChI

InChI=1S/C14H11BrO/c1-10(16)11-2-4-12(5-3-11)13-6-8-14(15)9-7-13/h2-9H,1H3

InChIKey

UUVKNCRMWPNBNM-UHFFFAOYSA-N

SMILES

C(=O)(C1=CC=C(C2=CC=C(Br)C=C2)C=C1)C

CAS DataBase Reference

5731-01-1(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi,N

Risk Statements 

36-51/53

Safety Statements 

26-36-61-24/25-22

RIDADR 

UN 3077 9/PG 3

WGK Germany 

3

HS Code 

2914790090

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

4-Acetyl-4'-bromobiphenyl Usage And Synthesis

Chemical Properties

White or pale brown solid

Uses

4-Acetyl-4'-bromobiphenyl is mainly used as a reagent for experimental organic synthesis or reactions, including substitution reactions or the synthesis and polymerisation of biphenyl derivatives.

Synthesis

Dichloromethane was added to Aluminium chloride. The mixture was stirred and cooled to 5 °C in a salt/ice bath. Acetyl chloride was quickly added through a dropping funnel and cooled to ? 3 °C to give a transparent yellow solution. Solid 4-bromobiphenyl was added in small amounts and stirred; wait for ? an hour, then add more. The mixture was stirred for ten hours, rising to 15 °C. The mixture was poured into a bucket of ice /37 percent HCl to destroy the aluminum chloride, then transferred to a separatory funnel and extracted into DCM. Then, the mixture was washed twice with water to destroy HCl. Again, it was washed with 10 percent NaOH and water. The collected DCM layer was dried over magnesium sulfate, mostly filtered by gravity. The solvent was removed in vacuo, and the residue was re-crystallized through ethanol to yield 4-Acetyl-4'-bromobiphen

References

[1] Journal of Molecular Liquids, 2012, vol. 175, p. 72 - 84
[2] Macromolecules, 2004, vol. 37, # 7, p. 2442 - 2449
[3] Molecular Crystals and Liquid Crystals Science and Technology, Section A: Molecular Crystals and Liquid Crystals, 1992, vol. 213, p. 187 - 206
[4] Journal of the Chemical Society, 1934, p. 869,871
[5] Journal of the Chemical Society [Section] C: Organic, 1966, p. 840 - 845

4-Acetyl-4'-bromobiphenyl(5731-01-1)Related Product Information

• 4'-Hydroxy-4-biphenylcarboxylic acid
• 4-Bromobiphenyl
• 4-Acetylbiphenyl
• Vat Orange 1
• 4-BENZOYL-4'-BROMOBIPHENYL
• 1-(4'-Bromobiphenyl-4-yl)-3-phenylpropenone
• 2-BROMO-1-(4''-BROMO-1,1''-BIPHENYL-4-YL)ETHANONE
• 4-Acetyl-4'-bromobiphenyl