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20-Deoxyingenol 3-angelate

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20-Deoxyingenol 3-angelate Basic information

Product Name:
20-Deoxyingenol 3-angelate
Synonyms:
  • 20-Deoxyingenol 3-angelate
  • 3-Angelyl-20-deoxyingenol
  • Euphorbia factor H8
  • PEP 006
  • 2-Butenoic acid, 2-methyl-, (1aR,2S,5R,5aS,6S,8aS,9R,10aR)-1a,2,5,5a,6,9,10,10a-octahydro-5,5a-dihydroxy-1,1,4,7,9-pentamethyl-11-oxo-1H-2,8a-methanocyclopenta[a]cyclopropa[e]cyclodecen-6-yl ester, (2Z)-
CAS:
75567-38-3
MF:
C25H34O5
MW:
414.53
Mol File:
75567-38-3.mol
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20-Deoxyingenol 3-angelate Usage And Synthesis

Uses

20-Deoxyingenol 3-angelate (DI3A) increases degranulation and interferon-gamma secretion of NK cells. 20-Deoxyingenol 3-angelate enhances NK cell tumoricidal activity[1].

References

[1] Zihang Xu, et al. A high-throughput assay for screening natural products that boost NK cell-mediated killing of cancer cells. Pharm Biol. 2020, 58, 1. DOI:10.1080/13880209.2020.1748661

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