(3R,4S)-1-(3-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one Chemical Properties

Boiling point:

652.9±55.0 °C(Predicted)

Density 

1.334±0.06 g/cm3(Predicted)

solubility 

DMSO (Slightly), Methanol (Slightly)

pka

9.72±0.30(Predicted)

form 

Solid

color 

White to Off-White

InChIKey

QAWZOIHXNLVZMK-XPWALMASSA-N

SMILES

N1(C2=CC=CC(F)=C2)[C@H](C2=CC=C(O)C=C2)[C@@H](CC[C@@H](C2=CC=C(F)C=C2)O)C1=O

(3R,4S)-1-(3-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one Usage And Synthesis

Uses

N-Des(4-Fluorophenyl)-N-(3-fluorophenyl)-ezetimibe is a derivative of Ezetimibe (E975000), which is an antihyperlipoproteinemic and a cholesterol absorption inhibitor.

(3R,4S)-1-(3-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one(1700622-06-5)Related Product Information

• ent-EzetiMibe
• 3-[5-(1,5-Dioxo-5-(p-fluophenylpentyl]-4R-phenyl-2-oxazolidinone
• 3-O-Acetyl Ezetimibe
• EzetiMibe LactaM Cleaved Alcohol
• EzetiMibe Fluoro IsoMer
• (3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(benzyloxy)phenyl]-3-azetidinepropanoic acid
• Ezetimibe Impurity
• Ezetimibe Impurity 54
• EZETIMIBE-D4
• 4-BENZYLIDENEAMINOPHENOL
• Ezetimibe Impurity 70
• 4-p-toluoylbutyricacid
• (R)-3-((S)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one
• EzetiMibe (3R,4R,3'S)-IsoMer
• 5-(4-FLUOROPHENYL)VALERIC ACID
• (4S)-3-[5-(4-Fluorophenyl)-1,5-dioxopenyl]-4-phenyl-2-oxazolidinone
• Ezetimibe Impurity 79
• Ezetimibe Impurity 38