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ent-Ivabradine Hydrochloride

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ent-Ivabradine Hydrochloride Basic information

Product Name:
ent-Ivabradine Hydrochloride
Synonyms:
  • ent-Ivabradine Hydrochloride
  • Ivabradine R-Isomer HCl
  • 3-[3-[[[(7R)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one
  • Ivabradine R-Isomer hydrochloride
  • I-3015
  • Ivabradine HCl R-Isomer
  • 3,3'-(propane-1,3-diyl)bis(7,8-dimethoxy-1H-benzo[d]azepin-2(3H)-one)
  • IIvabradine R-Isomer HCl
CAS:
148849-68-7
MF:
C27H37ClN2O5
MW:
505.05
Mol File:
148849-68-7.mol
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ent-Ivabradine Hydrochloride Chemical Properties

solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
White to Light Beige
Stability:
Hygroscopic
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ent-Ivabradine Hydrochloride Usage And Synthesis

Uses

3,3''-(Propane-1,3-diyl)bis(7,8-dimethoxy-1H-benzo[d]azepin-2(3H)-one) is an impurity of 3,3''-(Propane-1,3-diyl)bis(7,8-dimethoxy-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one) (P760340); an impurity in the synthesis of Ivabradine (I940500) which is a selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node. Also antianginal.

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