4-Ethyl-2,3-dioxo-1-piperazine carbonyl chloride Chemical Properties

Melting point:

100 °C

Boiling point:

292.9±23.0 °C(Predicted)

Density 

1.408±0.06 g/cm3(Predicted)

vapor pressure 

0Pa at 25℃

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

solubility 

Chloroform (Soluble), DMSO (Slightly)

form 

powder

pka

-1.81±0.20(Predicted)

color 

White

Water Solubility 

decomposes

Stability:

Moisture Sensitive

LogP

-1.48

CAS DataBase Reference

59703-00-3(CAS DataBase Reference)

Safety Information

Hazard Codes 

C

Risk Statements 

34

Safety Statements 

45-36/37/39-26

HS Code 

2933599590

MSDS

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4-Ethyl-2,3-dioxo-1-piperazine carbonyl chloride Usage And Synthesis

Chemical Properties

White to tan powder, partially agglomerated

Uses

4-Ethyl-2,3-dioxo-1-piperazinecarbonyl Chloride is used as a reagent in the synthesis of amino(thienyl)benzamide derivatives which are used as histone deacetylase inhibitors and have antitumor activity. 4-Ethyl-2,3-dioxo-1-piperazinecarbonyl Chloride is also a reagent in the synthesis of Cefbuperazone (C242540); a second-generation cephalosporin antibiotic.

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