5-NITROOXINDOLE Chemical Properties

Melting point:

233-236 °C

Boiling point:

411.4±45.0 °C(Predicted)

Density 

1.449±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

form 

solid

pka

12.61±0.20(Predicted)

color 

Beige

CAS DataBase Reference

20870-79-5(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38-43

Safety Statements 

26-36/37

WGK Germany 

3

Hazard Note 

Irritant/Keep Cold

HS Code 

2933790090

MSDS

• Language:English Provider:SigmaAldrich

5-NITROOXINDOLE Usage And Synthesis

Uses

• Reactant for synthesis of 3-[4-(amino/methylsulfonyl)phenyl]methylene-indolin-2-one derivatives as novel COX-1/2 and 5-LOX inhibitors
• Reactant for preparation of Aurora kinase inhibitors
• Reactant for synthesis of 3-substituted 2-indolinone RET inhibitors
• Reactant for synthesis of 4-azachromeno[2,3-b]indol-11(6H)-ones and derivatives as analogs of ellipticine
• Reactant for preparation of [18F]fluorobenzylidene-indolinone as possible tyrosine kinase inhibitor for PET tumor imaging
• Reactant for preparation of 3-substituted indolin-2-ones as neuroprotective and toxic agents

5-NITROOXINDOLE(20870-79-5)Related Product Information

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• 1-METHYL-5-NITRO-ISATIN
• 1-(2,4-DICHLOROBENZYL)-5-NITRO-3-[(PENTANOYLOXY)IMINO]-1,3-DIHYDRO-2H-INDOL-2-ONE
• AURORA 4248
• 1-(4-CHLOROBENZYL)-5-NITRO-1H-INDOLE-2,3-DIONE 3-OXIME
• 1-(4-CHLOROBENZYL)-5-NITRO-3-[(PENTANOYLOXY)IMINO]-1,3-DIHYDRO-2H-INDOL-2-ONE
• 1-(2,4-DICHLOROBENZYL)-5-NITRO-1H-INDOLE-2,3-DIONE
• 3-([(2-CHLOROACETYL)OXY]IMINO)-1-(4-CHLOROBENZYL)-5-NITRO-1,3-DIHYDRO-2H-INDOL-2-ONE
• 1-(4-CHLOROBENZYL)-3-([(2,2-DICHLOROACETYL)OXY]IMINO)-5-NITRO-1,3-DIHYDRO-2H-INDOL-2-ONE
• 1-(4-CHLOROBENZYL)-3-([(3-CHLOROPROPANOYL)OXY]IMINO)-5-NITRO-1,3-DIHYDRO-2H-INDOL-2-ONE
• 1-(4-CHLOROBENZYL)-3-([(3-METHYLBUTANOYL)OXY]IMINO)-5-NITRO-1,3-DIHYDRO-2H-INDOL-2-ONE
• 1-methyl-5-nitro-1,3-dihydro-2H-indol-2-one
• 7-METHYL-5-NITRO-1H-INDOLE-2,3-DIONE