N-(4-chlorophenyl)-2-(thiophen-2-yl)acetamide Chemical Properties

Melting point:

114-116 °C

Boiling point:

456.2±35.0 °C(Predicted)

Density 

1.363±0.06 g/cm3(Predicted)

pka

13.38±0.70(Predicted)

N-(4-chlorophenyl)-2-(thiophen-2-yl)acetamide Usage And Synthesis

Uses

JNK-IN-20 (compound 5) is a JNK inhibitor. JNK-IN-20 can be used in inflammation and tumor related research[1].

References

[1] Rückle T, et al. Design, synthesis, and biological activity of novel, potent, and selective (benzoylaminomethyl)thiophene sulfonamide inhibitors of c-Jun-N-terminal kinase. J Med Chem. 2004 Dec 30;47(27):6921-34. DOI:10.1021/jm031112e

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