N-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)-4-((2-methylpiperidin-1-yl)sulfonyl)benzamide Chemical Properties

Density 

1.390±0.06 g/cm3(Predicted)

pka

10.02±0.70(Predicted)

form 

Solid

color 

Light yellow to yellow

N-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)-4-((2-methylpiperidin-1-yl)sulfonyl)benzamide Usage And Synthesis

Uses

1650-M15 is an inhibitor of lipoteichoic acid synthase (LtaS). It has inhibitory activity against Gram-positive bacteria but has no significant inhibitory effect against Gram-negative bacteria. The IC50s of 1650-M15 against MRSA and MSSA are 62.44 μM and 66.42 μM, respectively, and the MICs are both 200 μM[1].

References

[1] Methods and compositions for inhibiting gram positive bacteria. United States, US20150246024 A1, 2015-09-03.

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