XTT sodium salt
XTT sodium salt Basic information
- Product Name:
- XTT sodium salt
- Synonyms:
-
- XTT sodium salt
- 2,3-Bis(2-methoxy-4-nitro-5-sulphophenyl)-2H-tetrazolium-5-carboxanilide inner salt
- SODIUM 3,3'-[1-[(PHENYLAMINO)CARBONYL]-3,4-TETRAZOLIUM]BIS (4-METHOXY-6-NITRO)BENZENE SULFONIC ACID HYDRATE
- SODIUM-3,3-[1-[(PHENYLAMINO)CARBONYL]-3,4-TETRAZOLIUM]-BIS(4-METHOXY-6-NITRO)BENZENE SULPHONIC ACID HYDRATE
- XTT
- xttsodium
- XTT (2,3-Bis-(2-methoxy-4-nitro-5-sulfophenyl) -2H-tetrazolium-5-carboxanilide)
- XTT SODIUM CELL CULTURE TESTED
- CAS:
- 111072-31-2
- MF:
- C22H18N7NaO13S2
- MW:
- 675.53
- EINECS:
- 601-039-1
- Product Categories:
-
- reagent
- Tetrazolium salt
- Mol File:
- 111072-31-2.mol
XTT sodium salt Chemical Properties
- Melting point:
- 285 ℃ (decompose)
- storage temp.
- 2-8°C
- solubility
- hot water: 2.5 mg/mL
- form
- powder
- color
- Yellow
- Water Solubility
- Soluble in hot water at 2.5mg/ml.Soluble in water, dimethyl sulfoxide, dimethyl formamide and phosphate buffered saline.at pH =7.2.
- λmax
- 286 nm
- Biological Applications
- Cell proliferation assays; cytotoxicity assays; ecotoxicity assays; neurotoxicity assays; antimicrobial susceptibility testing assays; antifungal susceptibility testing assays; cardiac valve viability assays; cell viability assay
- CAS DataBase Reference
- 111072-31-2(CAS DataBase Reference)
XTT sodium salt Usage And Synthesis
Uses
Tetrazolium derivative useful in cancer research.XTT sodium salt is used in conjunction with phenazine methosulfate to screen human cancer cell lines. It is also used to study fungal cell damage. It is involved in testing antimicrobial susceptibility of staphylococci and in candida biofilm research. Further, it is used in an assay for cell viability and cell proliferation.
Uses
Useful in AIDS and cancer testing.
General Description
XTT (sodium 3′-[1-[(phenylamino)-carbony]-3,4-tetrazolium]-bis(4-methoxy-6-nitro)benzene-sulfonic acid hydrate) is a tetrazolium salt, which forms water-soluble formazan on bioreduction.
Biochem/physiol Actions
XTT (sodium 3′-[1-[(phenylamino)-carbony]-3,4-tetrazolium]-bis(4-methoxy-6-nitro)benzene-sulfonic acid hydrate) is acted upon by dehydrogenases present in metabolically active cells. This produces water soluble formazan, which is a highly colored product. Thus, it offers an advantage in colorimetric proliferation assays, as opposed to MTT, as the product is already soluble and no formazan crystals are formed.
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XTT sodium salt(111072-31-2)Related Product Information
- Sodium bicarbonate
- CARBONYL SULFIDE
- Disodium edetate dihydrate
- Sodium hydroxide
- Diclofenac sodium
- Sodium sulfate
- Sodium benzoate
- Chlorophyllin
- 1H-Tetrazole-1-acetic acid
- 2,3,5-Triphenyltetrazolium chloride
- Nitrotetrazolium blue chloride
- PYRAZOPHOS
- Sodium chloride
- MCPA SODIUM
- Tetrazole
- Sodium 3-nitrobenzenesulphonate
- Sodium acetate
- 8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT