ACETOXYACETONE Chemical Properties

Melting point:

74.0-75.5 °C

Boiling point:

174-176 °C(lit.)

Density 

1.075 g/mL at 20 °C(lit.)

refractive index 

n20/D 1.415

Flash point:

71 °C

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

Soluble in diethyl ether, ethyl acetate and dichloromethane.

form 

Liquid

color 

Clear pale yellow to amber

Odor

fruity buttery dairy nutty

Odor Type

fruity

BRN 

1749857

LogP

-0.296 (est)

CAS DataBase Reference

592-20-1(CAS DataBase Reference)

EPA Substance Registry System

2-Propanone, 1-(acetyloxy)- (592-20-1)

Safety Information

Safety Statements 

23-24/25

WGK Germany 

3

TSCA 

Yes

HS Code 

29153900

MSDS

• Language:English Provider:SigmaAldrich

ACETOXYACETONE Usage And Synthesis

Chemical Properties

Clear pale yellow to amber liquid

Uses

Acetoxyacetone is an building block in the synthesis of various pharmaceutical and organic compounds.

Definition

ChEBI: Acetoxyacetone is a carboxylic ester and a ketone.

Synthesis Reference(s)

The Journal of Organic Chemistry, 57, p. 4263, 1992 DOI: 10.1021/jo00041a036

Purification Methods

Distil it in a vacuum, then redistil it at atmospheric pressure. It is miscible with H2O, but is slowly decomposed by it. Store it in a dry atmosphere. The 2,4-dinitrophenylhydrazone has m 115-115.5o (from CHCl3/hexane). [Perkin Jr J Chem Soc 59 789 1891, Reich & Samuels J Org Chem 21 68 1956, Nef Justus Liebigs Ann Chem 335 260 1904, Beilstein 2 IV 297.]

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