2-Naphthyl acetate Chemical Properties

Melting point:

67-70 °C (lit.)

Boiling point:

132 °C / 2mmHg

Density 

1.1032 (rough estimate)

refractive index 

1.6010 (estimate)

storage temp. 

-20°C

solubility 

methanol: 0.1 g/mL, clear

form 

powder to crystaline

color 

White to Light yellow

Sensitive 

Moisture Sensitive

BRN 

1868291

CAS DataBase Reference

1523-11-1(CAS DataBase Reference)

NIST Chemistry Reference

2-Naphthyl acetate(1523-11-1)

EPA Substance Registry System

2-Naphthalenol, acetate (1523-11-1)

Safety Information

Hazard Codes 

Xi

Risk Statements 

41

Safety Statements 

26-39

WGK Germany 

3

F 

10-21

TSCA 

Yes

HS Code 

2916399090

MSDS

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2-Naphthyl acetate Usage And Synthesis

Chemical Properties

WHITE FLUFFY POWDER

Uses

2-Naphthyl Acetate is used in the staining of gels for esterase activity in the biological laboratories. An esterase substrate.

Uses

2-Naphthyl acetate has been used as a substrate:

• in substrate sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) to examine the composition of lipases in larvae and adult specimens
• in the preparation of zymograms to identify proteins with lipase activity
• to measure non-specific esterase activity and β-esterase enzyme activity

Synthesis Reference(s)

Journal of the American Chemical Society, 91, p. 2162, 1969 DOI: 10.1021/ja01036a081

Purification Methods

Distil the acetate in a high vaccum and/or crystallise it from pet ether (b 60-80o) or dilute aqueous EtOH. The picrate has m 80o (from EtOH). [Beilstein 6 H 644, 6 I 313, 6 II 600, 5 III 2982, 6 IV 4267.]

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