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TRANS-3-HYDROXY-L-PROLINE

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TRANS-3-HYDROXY-L-PROLINE Basic information

Product Name:
TRANS-3-HYDROXY-L-PROLINE
Synonyms:
  • TRANS-3-HYDROXY-L-PROLINE
  • (2S,3S)-3-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID
  • H-3-HYP-OH
  • L-3-TRANS-HYDROXYPROLINE
  • L-3-HYDROXYPROLINE
  • H-HYP(3)-OH
  • H-PRO(3-HYDROXY)-OH
  • trans-3-Hydroxy-prolin
CAS:
4298-08-2
MF:
C5H9NO3
MW:
131.13
Product Categories:
  • Heterocycles
  • Pyrrolidine series
  • fine chemicals
Mol File:
4298-08-2.mol
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TRANS-3-HYDROXY-L-PROLINE Chemical Properties

Melting point:
235 °C
Boiling point:
242.42°C (rough estimate)
Density 
1.395
refractive index 
1.4300 (estimate)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
soluble in No data available
pka
2.03±0.40(Predicted)
Appearance
Off-white to light yellow Solid
optical activity
-15.667°(C=0.01g/ml H2O)
InChI
InChI=1S/C5H9NO3/c7-3-1-2-6-4(3)5(8)9/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4-/m0/s1
InChIKey
BJBUEDPLEOHJGE-IMJSIDKUSA-N
SMILES
C(O)(=O)[C@@H]1[C@@H](O)CCN1
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Safety Information

Safety Statements 
22-24/25
WGK Germany 
3
10
HS Code 
29339980

MSDS

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TRANS-3-HYDROXY-L-PROLINE Usage And Synthesis

Chemical Properties

White to light beige powder

Uses

trans-3-Hydroxyproline, is a versatile building block, used in the synthesis of various pharmaceutical and biologically active compounds. It is used as an intermediate in the synthesis of ferrocene-hydroxyproline amino acid conjugates.

Definition

ChEBI: Trans-3-hydroxy-L-proline is the (3S)-trans-diastereomer of 3-hydroxy-L-proline. It has a role as a metabolite. It is a tautomer of a trans-3-hydroxy-L-proline zwitterion.

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