3,4-Dimethylbenzophenone Chemical Properties

Melting point:

45-47 °C (lit.)

Boiling point:

335°C

Density 

1.0232 (rough estimate)

refractive index 

1.5361 (estimate)

Flash point:

>230 °F

storage temp. 

Sealed in dry,Room Temperature

solubility 

soluble in Methanol

form 

powder to crystal

color 

White to Light yellow

BRN 

1952043

InChI

InChI=1S/C15H14O/c1-11-8-9-14(10-12(11)2)15(16)13-6-4-3-5-7-13/h3-10H,1-2H3

InChIKey

JENOLWCGNVWTJN-UHFFFAOYSA-N

SMILES

C(C1=CC=C(C)C(C)=C1)(C1=CC=CC=C1)=O

CAS DataBase Reference

2571-39-3(CAS DataBase Reference)

NIST Chemistry Reference

3,4-Dimethylbenzophenone(2571-39-3)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-37/39-24/25-22-36

WGK Germany 

3

HS Code 

29143990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

3,4-Dimethylbenzophenone Usage And Synthesis

Description

3,4-Dimethylbenzophenone is an important chemical material for organic synthesis or laboratory research.

Synthesis

The general procedure for the synthesis of 3,4-dimethylbenzophenone from the compound (CAS: 65614-94-0) was carried out as follows: a magnetic stirrer was added to a Schlenk tube which had been pre-dried in an oven, and 1,2-diarylalkyn-1 (0.5 mmol), aniline (0.6 mmol), K2CO3 (0.5 mmol) and Cu(OAc)2 (0.075 mmol). Subsequently, DMSO (3 mL) was added as solvent, the reaction tube was sealed and purged by passing oxygen through a syringe. The reaction mixture was placed in an oil bath at 120 °C and the reaction was continuously stirred for 16-18 hours. Upon completion of the reaction, the reaction mixture was diluted with ethyl acetate (30 mL) and filtered through a diatomaceous earth pad. The organic phase was collected and washed sequentially with saturated NaCl solution (8 mL), saturated NH4Cl solution (8 mL) and again saturated NaCl solution (8 mL). The organic layer was dried over anhydrous Na2SO4 and concentrated under reduced pressure to remove the solvent to obtain the crude product. Finally, the crude product was purified by silica gel column chromatography (eluent: hexane/ethyl acetate gradient) to obtain the target compound 3,4-dimethylbenzophenone.

References

[1] RSC Advances, 2015, vol. 5, # 1, p. 690 - 693
[2] Tetrahedron, 2015, vol. 71, # 7, p. 1045 - 1049

3,4-Dimethylbenzophenone(2571-39-3)Related Product Information

• 3,4-Dihydroxybenzophenone
• Phenylhydrazine
• Bis(4-fluorophenyl)-methanone
• 4-Methylbenzophenone
• 3,4-Dimethylaniline
• PHENYL VALERATE
• Benzophenone hydrazone
• 3-Methylbenzophenone
• 2-Methylbenzophenone
• 1,3-Dimethylbarbituric acid
• Acetaldehyde
• 2,4-Dimethyl aniline
• Benzophenone oxime
• (3,4-Diaminophenyl)phenylmethanone
• 4,4'-Dihydroxybenzophenone
• Benzophenone
• 3,3',4,4'-Benzophenonetetracarboxylic dianhydride
• 2,3,4,5,6-PENTAMETHYLBENZOPHENONE