8H-Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizin-8-one, 5,6-dihydro-11,12-dimethoxy Chemical Properties

Melting point:

230-231 °C

Boiling point:

619.4±55.0 °C(Predicted)

Density 

1.44±0.1 g/cm3(Predicted)

storage temp. 

Store at -20°C

solubility 

Soluble in DMSO

pka

-1.63±0.20(Predicted)

8H-Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizin-8-one, 5,6-dihydro-11,12-dimethoxy Usage And Synthesis

Uses

8-Keto-berberine (compound 29) is a non-naturally occurring 11, 12-oxygenated protoberberine derived from naturally occurring 9, 10-oxygenated protoberberine[1].

References

[1] Miyoji Hanaoka, et al. Chemical transformation of protoberberines. VI. Ring D inversion of protoberberine alkaloids. Conversion of berberine into nonnaturally occurring 11,12-oxygenated protoberberines via spirobenzylisoquinolines. Chem.Pharm.Bull.1984;32(11):4431-4436.

8H-Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizin-8-one, 5,6-dihydro-11,12-dimethoxy(81397-08-2)Related Product Information

• berberrubine
• Palmatine chloride
• BERBAMINE
• phellodendrine
• Berberine
• DeMethyleneberberine
• BERLAMBINE
• BERBERINE ACID SULFATE
• Palmatine