BERBERINE ACID SULFATE
BERBERINE ACID SULFATE Basic information
- Product Name:
- BERBERINE ACID SULFATE
- Synonyms:
-
- berberine hydrogen sulphate
- Berbamine sulphate acid
- BERBERINE SULFATE(RG)
- BERBERINE SALTS/TENNATE /HCL/B-SULPHATE/SULPHATE
- berberinesulfate(1:1)
- siarczanuberberyny
- Benzo[G]-1,3-benzodioxolo[5,6-A]quinolizinium, 5,6-dihydro-9,10-dimethoxy-, sulfate
- Benzo[G]-1,3-benzodioxolo[5,6-A]quinolizinium, 5,6-dihydro-9,10-dimethoxy-, sulfate (1:1)
- CAS:
- 633-66-9
- MF:
- C20H19NO8S
- MW:
- 433.43
- EINECS:
- 211-196-4
- Product Categories:
-
- Alkaloids
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Mol File:
- 633-66-9.mol
BERBERINE ACID SULFATE Chemical Properties
- Melting point:
- 274-275 °C (decomp)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Powder
- color
- White to yellow
- Stability:
- Hygroscopic
BERBERINE ACID SULFATE Usage And Synthesis
Uses
Berberine Sulfate is an isoquinoline alkaloid with chemopreventative properties. It is used in the preparation of derivatives showing activity against leishmaniasis and malaria.
Chemical Properties
Yellow needle-shaped crystals. Odorless, extremely bitter. MP 274°C. Soluble in water (1:30) and ethanol.
Uses
Berberine Sulfate is an isoquinoline alkaloid with chemopreventative properties. It is used in the preparation of derivatives showing activity against leishmaniasis and malaria.
in vivo
Berberine sulfate (10, 30, or 50 mg/kg/day; gastrointestinal gavage; for 10 consecutive days) inhibits the growth of human colorectal adenocarcinoma in vivo. Berberine at doses of 30 and 50 mg/kg/day taken by gastrointestinal gavage shows inhibitory rates of 33.1% and 45.3% on the human colorectal adenocarcinoma xenograft growth in nude mice[1].
| Animal Model: | 5-week-old BALB/c nu/nu mice with human colorectal adenocarcinoma LoVo xenografts[1] |
| Dosage: | 10, 30, or 50 mg/kg/day |
| Administration: | Gastrointestinal gavage; for 10 consecutive days |
| Result: | Showed inhibitory rates of 33.1% and 45.3% at doses of 30 and 50 mg/kg/day. |
BERBERINE ACID SULFATE Preparation Products And Raw materials
Raw materials
BERBERINE ACID SULFATESupplier
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BERBERINE ACID SULFATE(633-66-9)Related Product Information
- BERLAMBINE
- phellodendrine
- Palmatine chloride
- Sodium tetraphenylboron
- Zinc hydroxide
- BERBAMINE DIHYDROCHLORIDE
- berberrubine
- Berberine hydrochloride
- Berberine
- BERBAMINE
- Palmatine
- DeMethyleneberberine
- 8H-Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizin-8-one, 5,6-dihydro-11,12-dimethoxy
- BERBERINE ACID SULFATE
- BERBERINE SULFATE TRIHYDRATE
- Berberine Bisulfate