1,3-Thiazole-2-carbaldehyde Chemical Properties

Boiling point:

61-63 °C/15 mmHg (lit.)

Density 

1.288 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.574(lit.)

Flash point:

154 °F

storage temp. 

2-8°C

form 

Liquid

pka

0.44±0.10(Predicted)

color 

Colorless to pale yellow

Water Solubility 

soluble

InChIKey

ZGTFNNUASMWGTM-UHFFFAOYSA-N

LogP

0.602 (est)

CAS DataBase Reference

10200-59-6(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

36/37/38-22

Safety Statements 

36/37/39-26-23-36

WGK Germany 

3

Hazard Note 

Harmful

HS Code 

29349990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

1,3-Thiazole-2-carbaldehyde Usage And Synthesis

Chemical Properties

Colorless to light yellow liqui

Uses

2-Thiazolecarboxaldehyde is a useful building block for taxane analogs.

Synthesis Reference(s)

Synthesis, p. 998, 1987 DOI: 10.1055/s-1987-28146

General Description

2-Thiazolecarboxaldehyde is a thiazole aldehyde derivative. It undergoes Baylis–Hillman reaction with methyl acrylate catalyzed by DABCO (1,4-diazabicyclo[2.2.2]octane). The reaction mechanism has been studied by electrospray ionization mass spectrometry (ESI-MS).

1,3-Thiazole-2-carbaldehyde(10200-59-6)Related Product Information

• 2-Acetylthiazole
• 2-(Trimethylsilyl)thiazole
• 2-Thiazolesulfonamide(9CI)
• Ethyl thiazole-2-carboxylate
• THIAZOLE-2-CARBOTHIOIC ACID AMIDE
• THIAZOLE-2-CARBOXYLIC ACID HYDRAZIDE
• ETHYL 1,3-BENZOTHIAZOLE-2-CARBOXYLATE
• 6-METHOXYBENZOTHIAZOLE-2-CARBOXAMIDE
• Benzothiazole-2-carboxaldehyde
• 4-Phenylthiazole-2-carboxylic acid
• (4-FORMYLTHIAZOL-2-YL)CARBAMIC ACID TERT-BUTYL ESTER
• 4-CHLORO-2-PIPERIDIN-1-YL-1,3-THIAZOLE-5-CARBALDEHYDE,4-CHLORO-2-PIPERIDIN-1-YL-THIAZOLE-5-CARBALDEHYDE
• 2-Bromo-4-fomylthiazole
• 2-Amino-5-formylthiazole
• 4-METHYL-THIAZOLE-5-CARBALDEHYDE
• 4-METHYL-2-[4-(TRIFLUOROMETHYL)PHENYL]-1,3-THIAZOLE-5-CARBALDEHYDE
• 4,5-THIAZOLEDICARBOXALDEHYDE
• 4-BROMO-2-FORMYLTHIAZOLE