N-Glycolylneuraminic acid Chemical Properties

Melting point:

188-190°C

Boiling point:

836.8±65.0 °C(Predicted)

Density 

1.670±0.06 g/cm3(Predicted)

storage temp. 

-20°C

solubility 

Water (Sparingly)

form 

Solid

pka

2.41±0.54(Predicted)

color 

White to Off-White

biological source

synthetic

Water Solubility 

water: soluble 20mg/mL

BRN 

1716828

InChI

InChI=1S/C11H19NO10/c13-2-5(16)8(18)9-7(12-6(17)3-14)4(15)1-11(21,22-9)10(19)20/h4-5,7-9,13-16,18,21H,1-3H2,(H,12,17)(H,19,20)/t4-,5+,7+,8+,9+,11-/m0/s1

InChIKey

FDJKUWYYUZCUJX-AJKRCSPLSA-N

SMILES

C(O)(=O)[C@@]1(C[C@H](O)[C@@H](NC(CO)=O)[C@H]([C@@H]([C@@H](CO)O)O)O1)O

CAS DataBase Reference

1113-83-3(CAS DataBase Reference)

Safety Information

Safety Statements 

24/25

WGK Germany 

3

F 

10

HS Code 

29329990

N-Glycolylneuraminic acid Usage And Synthesis

Chemical Properties

White Crystalline Solid

Uses

Glycolylneuraminic acid, a component of non-human milk and colostrums, is used as a reference to analyse changes of the glycome during lactation. Glycolylneuraminic acid, a xenoantigen, is involved in antigenic reactions (antibody-mediated hyperacute rejection) during xenotransplantion.

Uses

Regulation of N-glycolylneuraminic acid biosynthesis in rat and mouse liver.

Definition

ChEBI: An N-acylneuraminic acid in which the acyl substituent on nitrogen is glycolyl and which has beta-configuration at the anomeric centre.

Biological Activity

N-Glycolylneuraminic acid (Neu5Gc) functions as an important tool for profiling anti-Neu5Gc antibodies and sialic acid-binding proteins.

N-Glycolylneuraminic acid(1113-83-3)Related Product Information

• Hyaluronic acid
• Stearic acid
• Folic acid
• cis-4-Hydroxy-L-proline
• Ethyl 2-(Chlorosulfonyl)acetate
• N-Acetylneuraminic acid
• Citric acid
• Ascoric Acid
• 2-O-(p-Nitrophenyl)-α-D-N-glycolylneuraminic Acid Methyl Ester
• 2-O-(p-Nitrophenyl)-α-D-N-glycolylneuraminic Acid
• 8-O-methyl-7,9-di-O-acetyl-N-glycolylneuraminic acid
• 2-O-(p-Nitrophenyl)-a-D-N-glycolylneuraminic Acid
• N-Glycolylneuraminic acid
• N-glycolylneuraminic acid-isooctaosylceramide
• (N-acetylneuraminosyl-(2--8)-N-glycolylneuraminic acid)gangliotetraosylceramide
• di-(N-glycolylneuraminic acid)ganglioside GD1b
• GM2 N-glycolylneuraminic acid ganglioside
• 4-O-acetyl-N-glycolylneuraminic acid