POLY-L-HISTIDINE HYDROCHLORIDE MW
POLY-L-HISTIDINE HYDROCHLORIDE MW Basic information
- Product Name:
- POLY-L-HISTIDINE HYDROCHLORIDE MW
- Synonyms:
-
- polyhistidine
- POLY-L-HISTIDINE HYDROCHLORIDE MW
- POLY-L-HISTIDINE MOL WT 5000-15000
- POLY-L-HISTIDINE, HYDROCHLORIDE*MW 15,00 0-50,000
- poly-L-HistidineMW5000-15000
- poly-L-histidine chloride
- Poly-L-histidine mol wt 5,000-25,000
- CAS:
- 26062-48-6
- MF:
- C6H9N3O2
- MW:
- 155.16
- Product Categories:
-
- Amino Acids
- Homopolymers
- Polyamino Acids
- Mol File:
- 26062-48-6.mol
POLY-L-HISTIDINE HYDROCHLORIDE MW Chemical Properties
- storage temp.
- -20°C
POLY-L-HISTIDINE HYDROCHLORIDE MW Usage And Synthesis
Uses
Poly-L-histidine has been used:
- as a polycation for the dispersion of multi-wall carbon nanotubes (MWCNTs)
- as a polyionic compound to investigate its ability to rupture extracellular enveloped virus membrane
- in screening its anti-prion activity in cell based and in vivo anti-prion assay
Definition
ChEBI: Histidine is an alpha-amino acid that is propanoic acid bearing an amino substituent at position 2 and a 1H-imidazol-4-yl group at position 3. It has a role as a metabolite. It is an alpha-amino acid, a member of imidazoles, an aromatic amino acid and a polar amino acid. It contains a 1H-imidazol-4-ylmethyl group. It is a conjugate base of a histidinium(1+). It is a conjugate acid of a histidinate(1-).
General Description
Poly-L-histidine is an amphoteric compound. The imidazole ring in its structure enables protonation?deprotonation.
Biochem/physiol Actions
Poly-L-histidine (Phis) copolymers are biocompatible, pH responsive and are less toxic. It exhibits endolysosomal escape funcationality. The copolymer of Phis with poly(ethylene glycol)?poly(d,l-lactide) (PEG-PLA) is effective in delivering doxorubicin. pH sensitive poly(l-histidine) copolymer micelles have application in delivering anticancer drugs in acidic microenvironment.
POLY-L-HISTIDINE HYDROCHLORIDE MWSupplier
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
- Tel
- 010-010-010-62971590 18548936886
- jack@oka-vip.com
- Tel
- 0371-53736046 13393710386
- 2853979814@qq.com
- Tel
- 021-58432009 400-005-6266
- marketing1@energy-chemical.com
- Tel
- 027-027-59223056 18162699093
- 1208480011@qq.com