Azido-PEG7-acid
Azido-PEG7-acid Basic information
- Product Name:
- Azido-PEG7-acid
- Synonyms:
-
- N3-PEG7-CH2COOH
- N3-PEG7-CH2COOH/3,6,9,12,15,18,21-Heptaoxatricosanoic acid, 23-azido-
- CAS:
- 1446411-32-0
- MF:
- C16H31N3O9
- MW:
- 409.44
- Mol File:
- 1446411-32-0.mol
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Azido-PEG7-acid Usage And Synthesis
Biological Activity
Azido-PEG7-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Azido-PEG7-acidSupplier
Amatek Scientific Co. Ltd.
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