2-(4-Methylphenyl)ethanol Chemical Properties

Boiling point:

244-245 °C(lit.)

Density 

0.978 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.526(lit.)

Flash point:

225 °F

storage temp. 

Sealed in dry,Room Temperature

form 

clear liquid

pka

14.92±0.10(Predicted)

Specific Gravity

0.978

color 

Colorless to Light yellow to Light orange

Odor

at 100.00 %. floral balsamic rose green

Odor Type

floral

InChI

InChI=1S/C9H12O/c1-8-2-4-9(5-3-8)6-7-10/h2-5,10H,6-7H2,1H3

InChIKey

DAVFJRVIVZOKKS-UHFFFAOYSA-N

SMILES

C1(CCO)=CC=C(C)C=C1

LogP

2.032 (est)

CAS DataBase Reference

699-02-5(CAS DataBase Reference)

EPA Substance Registry System

Benzeneethanol, 4-methyl- (699-02-5)

Safety Information

Safety Statements 

24/25

WGK Germany 

3

TSCA 

Yes

HS Code 

29062990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

2-(4-Methylphenyl)ethanol Usage And Synthesis

Description

2-(4-Methylphenyl)ethanol, also known as 4-Methylphenethyl alcohol, 2-(p-Tolyl)ethanol, is an oily liquid that can promote bile secretion and protect the liver. It is capable of transporting fat from the liver to the extrahepatic fat pool via the bloodstream and has demonstrated a significant inhibitory effect on liver cell destruction caused by alcoholism.

Chemical Properties

Colorless to faintly Light yellow to Light orange clear liquid.

Uses

4-Methylphenethyl alcohol was used in the determination of adducts of 1,2- and 1,4-benzoquinone with cysteine residues of hemoglobin and albumin.

Preparation

To prepare 2-(4-Methylphenyl)ethanol, start with 4'-Methylacetophenone as the raw material. Reduce it to 4-methyl-α-phenylethanol using sodium borohydride in ethanol. Mix nicotinic acid with phosphorus oxychloride in pyridine to create nicotinyl chloride. Without separation, add the nicotinyl chloride to the 4-methyl-α-phenylethanol and esterify it into 2-(4-Methylphenyl)ethanol.?

2-(4-Methylphenyl)ethanol(699-02-5)Related Product Information

• 4-Methylphenylacetic acid
• 4-(2-HYDROXYETHYL)BENZONITRILE
• ETHYL MESITYLACETATE
• 2-(4-Methylphenyl)ethanol
• ETHYL P-TOLYLACETATE
• 1,4-Phenylenediacetic acid
• 4-Biphenylacetic acid
• 2,4-BIS(TRIFLUOROMETHYL)PHENYLACETIC ACID
• 4-(Trifluoromethyl)phenylacetic acid
• 2-MESITYLETHANOL
• 4-(TRIFLUOROMETHYL)MANDELIC ACID
• MESITYLACETIC ACID
• 4-ISOPROPYLPHENYLACETIC ACID
• 4-(BROMOMETHYL)PHENYLACETIC ACID
• Ibuprofen
• 1-(P-TOLYL)-1-CYCLOPENTANECARBOXYLIC ACID
• Methyl p-tert-butylphenylacetate
• 2,5-DIHYDROXY-1,4-BENZENEDIACETIC ACID