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Myristicin

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Myristicin Basic information

Product Name:
Myristicin
Synonyms:
  • myristicinfromparsleyleafoil
  • MYRISTICIN FROM PARSLEY OIL
  • MYRISTICIN(SG)
  • 5-methoxysafrole
  • MYRISTICIN WITH GC
  • 5-Allyl-2,3-(methylendioxy)anisole, 6-Allyl-4-methoxy-1,3-benzodioxole
  • 4-Methoxy-6-allyl-1,3-benzodioxole
  • 7-Methoxy-5-(2-propenyl)-1,3-benzodioxole
CAS:
607-91-0
MF:
C11H12O3
MW:
192.21
EINECS:
210-146-9
Product Categories:
  • Miscellaneous Natural Products
  • Aromatic Phenols
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Neurochemicals
  • Pharmaceuticals
Mol File:
607-91-0.mol
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Myristicin Chemical Properties

Melting point:
-20℃
Boiling point:
bp40 173°
Density 
d2020 1.1437
refractive index 
nD20 1.54032
storage temp. 
2-8°C
solubility 
Soluble in acetone, ethanol and methanol;
form 
oil
color 
clear, light yellow
Odor
at 100.00 %. spicy warm balsamic woody
Odor Type
spicy
Water Solubility 
insoluble in water
BRN 
166218
Stability:
Light Sensitive
LogP
2.586 (est)
CAS DataBase Reference
607-91-0(CAS DataBase Reference)
NIST Chemistry Reference
1,3-Benzodioxole, 4-methoxy-6-(2-propenyl)-(607-91-0)
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Safety Information

Risk Statements 
52/53
Safety Statements 
61
RIDADR 
UN 3082 9/PG 3
WGK Germany 
1
RTECS 
CY2625000
10-23
Hazardous Substances Data
607-91-0(Hazardous Substances Data)
Toxicity
A naturally occurring methylenedioxyphenyl compound found in nutmeg. It has been suggested that myristicin may be responsible, in whole or in part, for the toxicity of nutmeg. The spice (5-15 g) causes symptoms similar to atropine poisoning: flushing of the skin, tachycardia, absence of salivation, and excitation of the CNS. Euphoria and hallucinations have given rise to abuse of this material. As a methylenedioxyphenyl compound, myristicin gives rise to a type III spectrum with reduced cytochrome P450 and can inhibit monooxygenations catalyzed by this cytochrome.

MSDS

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Myristicin Usage And Synthesis

Description

Myristicin is an alkenylbenzene present in small amounts in the essential oil of nutmeg that is reported to act as a serotonin receptor antagonist, a weak monamine oxidase inhibitor, and to produce hallucinogenic effects. Abuse of myristicin has led to fatal poisoning, which has prompted improved methods for HPLC determination of myristicin in human plasma. This product is intended for forensic and research purposes.

Chemical Properties

Crystalline phenolic ether with a strongodor.

Uses

A naturally occurring insecticide and acaricide with possible neurotoxic effects on neuroblastoma cells

Definition

The chief substance inthe ripe seeds of nutmeg (Myristica fragrans).It reduces the levels of cytochrome p-450 andinhibits monooxygenations catalyzed by thisenzyme.

Hazard

Poison; moderately toxic; mutagen.

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