MONOMYRISTIN Chemical Properties

Melting point:

68-70 °C

Boiling point:

363.47°C (rough estimate)

Density 

0.9748 (rough estimate)

refractive index 

1.4230 (estimate)

storage temp. 

Sealed in dry,2-8°C

solubility 

very faint turbidity in Methanol

form 

powder to crystal

pka

13.16±0.20(Predicted)

color 

White to Almost white

biological source

synthetic (organic)

BRN 

1727502

Dielectric constant

6.1（70℃）

InChI

InChI=1S/C17H34O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-17(20)21-15-16(19)14-18/h16,18-19H,2-15H2,1H3

InChIKey

DCBSHORRWZKAKO-UHFFFAOYSA-N

SMILES

C(OCC(O)CO)(=O)CCCCCCCCCCCCC

EPA Substance Registry System

1-Monomyristin (589-68-4)

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

HS Code 

2915.90.5050

MSDS

• Language:English Provider:SigmaAldrich

MONOMYRISTIN Usage And Synthesis

Description

1-Monomyristin is a 1-monoglyceride with tetradecanoyl (myristoyl) as the acyl group. 1-Monomyristin has a role as a Caenorhabditis elegans metabolite. 1-Monomyristin is a 1-monoglyceride and a tetradecanoate ester.
1-Monomyristin, extracted from Serenoa repens, inhibits the hydrolysis of 2-oleoylglycerol (IC50=32 μM) and fatty acid amide hydrolase (FAAH) activity (IC50=18 μM). 1-Monomyristin shows antibacterial activity against Staphylococcus aureus and Aggregatibacter actinomycetemcomitans and also antifungal activity against Candida albicans.

Chemical Properties

It is soluble in organic solvents such as methanol, ethanol, and DMSO, and is derived from nutmeg.

Uses

α-Monomyristin, is used for the preparation of nonionic surfactant micelles. It is also a 1-monoglyceride of myristic acid, has antibacterial activity against several Gram-positive bacterial strains.

Definition

ChEBI: A rac-1-monoacylglycerol that is composed of equal amounts of 1-myristoyl-sn-glycerol and 3-myristoyl-sn-glycerol.

Biological Activity

rac-Glycerol 1-myristate also elicits antifungal activity. It exhibits an anti-proliferative effect in HeLa cervical cancer cells when delivered as a polymeric nanoparticle-based conjugate.', 'rac-Glycerol 1-myristate, a 1-monoglyceride of myristic acid, has antibacterial activity against several Gram-positive bacterial strains.

IC 50

Human Endogenous Metabolite

MONOMYRISTIN(589-68-4)Related Product Information

• Monoacetin
• MONOLAURIN
• Sorbitan monopalmitate
• Myristic acid
• Myristicin
• 1-Tetradecanol
• TRIMYRISTIN
• Cinnamic acid
• Linolenic acid
• gamma-Linolenic acid
• GLUCOTROPAEOLIN
• ALPHA-CARYOPHYLLENE
• 4-[(2R,3R)-2,3-Dihydro-7-methoxy-3-methyl-5-[(E)-1-propenyl]benzofuran-2-yl]-2-methoxyphenol
• METHYL LINOLENATE
• Valeric acid
• (aR)-alpha-[(1S)-1-[2,6-Dimethoxy-4-(2-propen-1-yl)phenoxy]ethyl]-4-hydroxy-3-methoxybenzenemethanol
• LINOLENIC ACID ETHYL ESTER
• Cinnamyl alcohol