MONOLAURIN Chemical Properties

Melting point:

63 °C

Boiling point:

186 °C / 1mmHg

Density 

0.9764 (rough estimate)

refractive index 

1.4350 (estimate)

storage temp. 

-20°C

solubility 

Practically insoluble in water

form 

powder to crystal

pka

13.16±0.20(Predicted)

color 

White to Almost white

biological source

plant

Water Solubility 

6mg/L

BRN 

1726740

Cosmetics Ingredients Functions

SKIN CONDITIONING - EMOLLIENT
SURFACTANT - EMULSIFYING

Cosmetic Ingredient Review (CIR)

MONOLAURIN (142-18-7)

InChI

1S/C15H30O4/c1-2-3-4-5-6-7-8-9-10-11-15(18)19-13-14(17)12-16/h14,16-17H,2-13H2,1H3

InChIKey

ARIWANIATODDMH-UHFFFAOYSA-N

SMILES

CCCCCCCCCCCC(=O)OCC(O)CO

LogP

4.029 (est)

CAS DataBase Reference

142-18-7(CAS DataBase Reference)

EPA Substance Registry System

1-Monolaurin (142-18-7)

Safety Information

WGK Germany 

1

RTECS 

OF1600000

TSCA 

TSCA listed

HS Code 

2918.19.9000

Storage Class

11 - Combustible Solids

MSDS

• Language:English Provider:SigmaAldrich

MONOLAURIN Usage And Synthesis

Uses

glyceryl laurate is a coemulsifier for oil-in-water emulsions. It is also a super fattening agent that promotes absorption and has a bacteriostatic effect.

Uses

Monolaurin has antibacterial, antiviral, and other antimicrobial effects in vitro.

Definition

ChEBI: 1-monolauroylglycerol is a 1-monoglyceride with dodecanoyl (lauroyl) as the acyl group. It is a 1-monoglyceride and a dodecanoate ester.

Synthesis Reference(s)

Synthetic Communications, 19, p. 2505, 1989 DOI: 10.1080/00397918908052653

Flammability and Explosibility

Non flammable

Biochem/physiol Actions

Monolaurin (1-Lauroyl-rac-glycerol) is used as an antimicrobial agent in various formulas and microemulsions and as a methane mitigation agent in ruminants.

Synthesis

(1)Use lower alcohol Na or lower alcohol potassium as catalyst, lower alcohol ester of lauric acid and glycerol mixed according to the molar ratio of 3:1, under the condition of 150-170 ?? vacuum reaction 20-40h to obtain glycerol ester of lauric acid crude product;

(2)Use 40-50% of the weight of the crude product of glycerol ester of fatty lauric acid, mass fraction of 4%-10% of the aqueous citric acid to wash fatty acid glycerol ester of crude product once, and then Add 30% -50% of the weight of crude glyceryl laurate 80-100 ?? C hot water, stirred well, static stratification, separation of the upper layer of oil, and then 80-100 ?? C hot water, water wash 3 times, heating and depressurization to remove water;

(3) in the temperature of 130-220 ?? C, the vacuum degree of 0.1-150pa under the conditions of molecular distillation of the product of the said step (2) to get the product of the glyceryl laurate. Glyceryl laurate product.

MONOLAURIN(142-18-7)Related Product Information

• Lauric acid
• Lauryl betaine
• Myrcene
• Sodium lauryl sulfoacetate
• VINYL LAURATE
• N-SUCCINIMIDYL PALMITATE
• POTASSIUM LAURATE
• PROPYL LAURATE
• BUTYL LAURATE
• gelucire 44-14
• 2-ethylhexyl laurate
• Dodecanoic acid, 2-[4-(phenylMethoxy)phenyl]ethyl ester
• octyl laurate
• isooctyl laurate
• ISOPROPYL LAURATE
• METHYL LAURATE
• Ethyl laurate
• Pregnenolone acetate